Species

KNApSAcK Entry

Organism name Streptomyces griseochromogenes RS-1223
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00017650 External link 512 Tautomycetin
CHEMBL1366322
C058744
7 / 7 / 6 0 / 1 No. 5743

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10828 Thyroid hormone receptor beta NR1A2 C00017650 3 / 1
P11473 Vitamin D3 receptor NR1I1 C00017650 2 / 3
O15296 Arachidonate 15-lipoxygenase B Enzyme C00017650 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00017650 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00017650 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00017650 2 / 2
Q9UBT6 DNA polymerase kappa Enzyme C00017650 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#119900 Digital clubbing, isolated congenital P15428
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (6)

KEGG name UniProt
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009410 Nerve Degeneration C00017650