| Organism name | Streptomyces No. NH435-hF3 |
|---|---|
| Genus | Streptomyces |
| Family | Streptomycetaceae |
| Kingdom | Bacteria |
| Linked NCBI taxonomy name | Streptomyces |
|---|---|
| Linked NCBI taxonomy ID | 1883 |
| Linked level | genus |
| Family in NCBI taxonomy | Streptomycetaceae |
|---|---|
| ID | 2062 |
| Kingdom (Superkingdom) in NCBI taxonomy | Bacteria |
|---|---|
| ID | 2 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00017751
|
MH 435A
/ Erbstatin / Antibiotic MH 435A |
CHEMBL47986
CHEMBL2001273 |
C048212
|
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|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00017751 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00017751 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00017751 | 2 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00017751 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00017751 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00017751 | 1 / 1 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00017751 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00017751 | 1 / 8 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00017751 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00017751 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00017751 | 0 / 0 |
| P07711 | Cathepsin L1 | C1A | C00017751 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00017751 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00017751 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00017751 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00017751 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00017751 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00017751 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00017751 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00017751 | 4 / 3 |
| Q9GZV3 | High affinity choline transporter 1 | Choline Na-symporter | C00017751 | 1 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00017751 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00017751 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00017751 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00017751 | 1 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00017751 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #211980 | Lung cancer |
P00533
|
| #158580 | Neuronopathy, distal hereditary motor, type viia; hmn7a |
Q9GZV3
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
|
| H00018 | Gastric cancer |
P00533
(related)
|
| H00022 | Bladder cancer |
P00533
(related)
|
| H00028 | Choriocarcinoma |
P00533
(related)
|
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|