Species

KNApSAcK Entry

Organism name Streptomyces lavendulae No. 314
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00017821 External link 512 Saframycin Yd 1
C046329
No. 550
C00017822 External link 512 Saframycin Yd 2
C046330
No. 550
C00017823 External link 512 Saframycin Ad 1
C051479
No. 550
C00018157 External link 512 NSC 325663
/ Saframycin A
/ (-)-Saframycin A
CHEMBL452709
CHEMBL1710157
C026925
9 / 10 / 3 No. 550
C00018158 External link 512 Saframycin B
C053948
No. 550
C00018299 External link 512 Saframycin S
C027443
No. 550
C00018159 External link 512 Saframycin C
C034205
No. 550
C00018161 External link 512 Saframycin E
C096067
No. 2673
C00018160 External link 512 Saframycin D
C052748
No. 2673
C00018482 External link 512 Saframycin R
No. 2673

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00018157 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00018157 2 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00018157 0 / 0
P37840 Alpha-synuclein Unclassified protein C00018157 4 / 2
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00018157 2 / 0
O75496 Geminin Unclassified protein C00018157 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00018157 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00018157 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00018157 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (3)

KEGG name UniProt
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)