| Organism name | Streptomyces filipinensis MD 157-A9 | 
|---|---|
| Genus | Streptomyces | 
| Family | Streptomycetaceae | 
| Kingdom | Bacteria | 
| Linked NCBI taxonomy name | Streptomyces | 
|---|---|
| Linked NCBI taxonomy ID | 1883 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Streptomycetaceae | 
|---|---|
| ID | 2062 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Bacteria | 
|---|---|
| ID | 2 | 
| Plant class | |
|---|---|
| ID | 
| KNApSAcK ID | name | ChEMBL link | CTD link | 
                        # of proteins in
                         ChEMBL interaction / related OMIM / related KEGG DISEASE  | 
                      
                        # of genes in
                         CTD interaction / related diseases  | 
                      
                        KCF-S
                         cluster  | 
                      
                        phytochemical
                         cluster  | 
                      figure | 
|---|---|---|---|---|---|---|---|---|
| 
                        C00018861
                        
                           | 
                      
                        Methylspinazarin
                         / Methylspinazaline  | 
                      
                        CHEMBL1474732
                         | 
                      
                        C008495
                         | 
                      9 / 11 / 15 | No. 2060 | 
                         
                       | 
                    ||
| 
                        C00017953
                        
                           | 
                      
                        Dihydromethylspinazaline
                         / 6,7-Dihydromethylspinazarin  | 
                      No. 8235 | 
                         
                       | 
                    
| accession | description | class description | KNApSAcK metabolite in interactions | 
                          # of diseases
                           (OMIM / KEGG)  | 
                      
|---|---|---|---|---|
| P11473 | Vitamin D3 receptor | NR1I1 | C00018861 | 2 / 3 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00018861 | 0 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00018861 | 2 / 2 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00018861 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00018861 | 4 / 3 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00018861 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00018861 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00018861 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00018861 | 1 / 2 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #119900 | Digital clubbing, isolated congenital | 
                            P15428
                             | 
                        
| #600274 | Frontotemporal dementia; ftd | 
                            P10636
                             | 
                        
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | 
                            Q03164
                             | 
                        
| #145000 | Hyperparathyroidism 1; hrpt1 | 
                            O00255
                             | 
                        
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | 
                            P15428
                             | 
                        
| #131100 | Multiple endocrine neoplasia, type i; men1 | 
                            O00255
                             | 
                        
| #607948 | Mycobacterium tuberculosis, susceptibility to | 
                            P11473
                             | 
                        
| #260540 | Parkinson-dementia syndrome | 
                            P10636
                             | 
                        
| #172700 | Pick disease of brain | 
                            P10636
                             | 
                        
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | 
                            P10636
                             | 
                        
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | 
                            P11473
                             | 
                        
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | 
                            O00255
                            (related)
                             | 
                        
| H00034 | Carcinoid | 
                            O00255
                            (related)
                             | 
                        
| H00045 | Malignant islet cell carcinoma | 
                            O00255
                            (related)
                             | 
                        
| H00246 | Primary hyperparathyroidism | 
                            O00255
                            (related)
                             | 
                        
| H01102 | Pituitary adenomas | 
                            O00255
                            (related)
                             | 
                        
| H00058 | Amyotrophic lateral sclerosis (ALS) | 
                            P10636
                            (related)
                             | 
                        
| H00077 | Progressive supranuclear palsy (PSP) | 
                            P10636
                            (related)
                             | 
                        
| H00078 | Frontotemporal lobar degeneration (FTLD) | 
                            P10636
                            (related)
                             | 
                        
| H00342 | Tuberculosis | 
                            P11473
                            (related)
                             | 
                        
| H00784 | Localized autosomal recessive hypotrichosis | 
                            P11473
                            (related)
                             | 
                        
| H01143 | Vitamin D-dependent rickets | 
                            P11473
                            (related)
                             | 
                        
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | 
                            P15428
                            (related)
                             | 
                        
| H01246 | Isolated congenital nail clubbing (ICNC) | 
                            P15428
                            (related)
                             | 
                        
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | 
                            Q03164
                            (related)
                             Q03164 (marker)  | 
                        
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | 
                            Q03164
                            (related)
                             |