Species

KNApSAcK Entry

Organism name Saccharopolyspora erythrea
Genus Saccharopolyspora
Family Pseudonocardiaceae
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Saccharopolyspora
Linked NCBI taxonomy ID 1835
Linked level genus

Family

Family in NCBI taxonomy Pseudonocardiaceae
ID 2070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00047195 External link 512 Borrelidin
CHEMBL70590
CHEMBL578929
CHEMBL1473901
CHEMBL1984032
C005066
11 / 11 / 10 No. 6626
C00018584 External link 512 Stigmatellin
CHEMBL486556
C041573
1 / 0 No. 7124

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00047195 1 / 1
P37840 Alpha-synuclein Unclassified protein C00047195 4 / 2
P11473 Vitamin D3 receptor NR1I1 C00047195 2 / 3
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00047195 2 / 0
O75496 Geminin Unclassified protein C00047195 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00047195 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00047195 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00047195 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00047195 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00047195 0 / 3
Q06710 Paired box protein Pax-8 Unclassified protein C00047195 1 / 2

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
6622 SNCA, NACP, PARK1, PARK4, PD1 synuclein, alpha (non A4 component of amyloid precursor) C00018584

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (10)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
Q06710 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00032 Thyroid cancer Q06710 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)