Species

KNApSAcK Entry

Organism name Streptomyces hygroscopicus E-749
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00018750 External link 512 X 464
/ Helixin C
/ Azalomycin M
/ Polyetherin A
/ Antibiotic M 2
/ Antibiotic X 464
/ Antibiotic K 178
CHEMBL174316
CHEMBL405862
CHEMBL1592173
CHEMBL2005417
D009550
4 / 5 / 5 1 / 1 No. 199

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00018750 4 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00018750 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00018750 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00018750 1 / 4

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
29952 DPP7, DPP2, DPPII, QPP dipeptidyl-peptidase 7 (EC:3.4.14.2) C00018750

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (5)

KEGG name UniProt
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009336 Necrosis C00018750