| Organism name | Streptomyces lomondensis var. lomondenssis |
|---|---|
| Genus | Streptomyces |
| Family | Streptomycetaceae |
| Kingdom | Bacteria |
| Linked NCBI taxonomy name | Streptomyces |
|---|---|
| Linked NCBI taxonomy ID | 1883 |
| Linked level | genus |
| Family in NCBI taxonomy | Streptomycetaceae |
|---|---|
| ID | 2062 |
| Kingdom (Superkingdom) in NCBI taxonomy | Bacteria |
|---|---|
| ID | 2 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00018764
|
Lomofungin
/ NSC 156939 / NSC 106995 / Lomondomycin |
CHEMBL1505471
|
C100203
|
27 / 18 / 15 | No. 6147 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00018764 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00018764 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00018764 | 2 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00018764 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00018764 | 3 / 1 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00018764 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00018764 | 1 / 2 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00018764 | 1 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00018764 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00018764 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00018764 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00018764 | 1 / 1 |
| Q99816 | Tumor susceptibility gene 101 protein | Unclassified protein | C00018764 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00018764 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00018764 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00018764 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00018764 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00018764 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00018764 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00018764 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00018764 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00018764 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00018764 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00018764 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00018764 | 1 / 2 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00018764 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00018764 | 2 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #210900 | Bloom syndrome; blm |
P54132
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|