Species

KNApSAcK Entry

Organism name Streptomyces tolypophorus nov. sp. No. B2847
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00018825 External link 512 NSC 177383
/ Tolypomycin Y
CHEMBL1589942
CHEMBL2004834
C003617
8 / 5 / 6 No. 5656

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018825 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018825 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00018825 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018825 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00018825 3 / 3
P16050 Arachidonate 15-lipoxygenase Enzyme C00018825 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018825 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018825 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)