Species

KNApSAcK Entry

Organism name Streptomyces sapporonensis WS 4545
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00018850 External link 512 Bicozamycin
/ Bicyclomycin
/ Antibiotic 5879
/ Antibiotic WS 4545
CHEMBL18621
CHEMBL352043
CHEMBL1358132
CHEMBL1976371
CHEMBL2103766
C024504
6 / 5 / 5 No. 8853

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018850 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00018850 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018850 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018850 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018850 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018850 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)