Ferula elaeochytris
Species
KNApSAcK Entry
| Organism name | Ferula elaeochytris |
|---|---|
| Genus | Ferula |
| Family | Apiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Ferula elaeochytris |
|---|---|
| Linked NCBI taxonomy ID | 662809 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apiaceae |
|---|---|
| ID | 4037 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (9)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00034208
|
Sandrosaponin IX
/ (+)-Sandrosaponin IX |
No. 4 | No. 51 |
|
||||
|
C00030807
|
Neochlorogenic acid
/ 5-Caffeoylquinic acid / 5-O-Caffeoylquinic acid |
CHEMBL284616
CHEMBL230481 CHEMBL249450 CHEMBL1332980 CHEMBL1394423 CHEMBL1419611 CHEMBL1473644 CHEMBL1552319 |
30 / 19 / 22 | No. 314 | No. 6 |
|
||
|
C00033573
|
6-(p-Hydroxybenzoyl)lancerotriol
/ Lancerotriol 6-(p-hydroxybenzoate) |
No. 327 |
|
|||||
|
C00021389
|
Ferutinin
/ Jaeschkeanadiol p-hydroxybenzoate |
CHEMBL465040
|
C111068
|
3 / 1 / 1 | No. 327 |
|
||
|
C00021386
|
Teferidin
|
CHEMBL516694
CHEMBL1999942 |
1 / 1 / 1 | No. 327 |
|
|||
|
C00033805
|
Elaeochytrin B
/ (+)-Elaeochytrin B |
No. 327 |
|
|||||
|
C00033804
|
Elaeochytrin A
/ (+)-Elaeochytrin A |
No. 327 |
|
|||||
|
C00021412
|
Jaeskeanin
/ Ferutinin alpha-epoxide / 6-(p-Hydroxybenzoyl)epoxyjaeschkeanadiol |
No. 971 |
|
|||||
|
C00033577
|
6-Angeloyljaeschkeanadiol
/ Jaeschkeanadiol 6-angelate |
No. 1621 |
|
Human Protein / Gene in interactions
33 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P03372 | Estrogen receptor | NR3A1 | C00021386 C00021389 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00030807 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00030807 | 0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00030807 | 2 / 2 |
| Q13093 | Platelet-activating factor acetylhydrolase | Enzyme | C00030807 | 3 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00030807 | 3 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00030807 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00030807 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00030807 | 0 / 0 |
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00030807 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00021389 | 0 / 1 |
| P15121 | Aldose reductase | Enzyme | C00030807 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00030807 | 0 / 0 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00030807 | 1 / 2 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00030807 | 0 / 1 |
| P12931 | Proto-oncogene tyrosine-protein kinase Src | Src | C00030807 | 0 / 0 |
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00030807 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00030807 | 3 / 3 |
| P51692 | Signal transducer and activator of transcription 5B | Unclassified protein | C00030807 | 1 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00021389 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00030807 | 1 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00030807 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00030807 | 0 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00030807 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00030807 | 0 / 0 |
| P19224 | UDP-glucuronosyltransferase 1-6 | Enzyme | C00030807 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00030807 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00030807 | 0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00030807 | 0 / 0 |
| P42224 | Signal transducer and activator of transcription 1-alpha/beta | Unclassified protein | C00030807 | 3 / 3 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00030807 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00030807 | 1 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00030807 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (20)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #600807 | Asthma, susceptibility to |
Q13093
|
| #209950 | Atypical mycobacteriosis, familial |
P42224
|
| #614162 | Candidiasis, familial, 7; candf7 |
P42224
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #245590 | Growth hormone insensitivity with immunodeficiency |
P51692
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #147050 | Ige responsiveness, atopic; iger |
Q13093
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613796 | Mycobacterial and viral infections, susceptibility to, autosomal recessive |
P42224
|
| #614278 | Platelet-activating factor acetylhydrolase deficiency; pafad |
Q13093
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
KEGG DISEASE (23)
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|
| H00016 | Oral cancer |
P40763
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00089 | IFN-gamma/IL-12 axis |
P42224
(related)
|
| H00363 | Candidiasis |
P42224
(related)
|
| H01109 | Chronic mucocutaneous candidiasis (CMC) |
P42224
(related)
|
| H00931 | Growth hormone insensitivity with immunodeficiency |
P51692
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|