Species

KNApSAcK Entry

Organism name Penicillium griseofulvum (a mutant strain)
Genus Penicillium
Family Trichocomaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Penicillium
Linked NCBI taxonomy ID 5073
Linked level genus

Family

Family in NCBI taxonomy Aspergillaceae
ID 1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00023983 External link 512 Norlichexanthone
/ 3,6,8-Trihydroxy-1-methylxanthone
CHEMBL466154
17 / 10 / 10 No. 71 No. 15

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q02750 Dual specificity mitogen-activated protein kinase kinase 1 Ste7 C00023983 1 / 1
P08069 Insulin-like growth factor 1 receptor TK tyrosine-protein kinase INSR subfamily C00023983 1 / 3
Q16512 Serine/threonine-protein kinase N1 Pkn C00023983 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00023983 0 / 0
Q05397 Focal adhesion kinase 1 Fak C00023983 0 / 0
P51955 Serine/threonine-protein kinase Nek2 Nek C00023983 0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily C00023983 1 / 1
O60285 NUAK family SNF1-like kinase 1 CAMK serine/threonine protein kinase NUAK subfamily C00023983 0 / 0
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00023983 0 / 0
Q96GD4 Aurora kinase B Aur C00023983 0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00023983 1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00023983 2 / 3
P53350 Serine/threonine-protein kinase PLK1 PLK serine/threonine protein kinase subfamily C00023983 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00023983 4 / 1
Q9HC98 Serine/threonine-protein kinase Nek6 Nek C00023983 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00023983 0 / 1
P30530 Tyrosine-protein kinase receptor UFO TK tyrosine-protein kinase AXL subfamily C00023983 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#114480 Breast cancer P31749
#615279 Cardiofaciocutaneous syndrome 3; cfc3 Q02750
#114500 Colorectal cancer; crc P31749
#615109 Cowden syndrome 6; cws6 P31749
#602089 Hemangioma, capillary infantile P35968
#114550 Hepatocellular carcinoma P08581
#270450 Insulin-like growth factor i, resistance to P08069
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73
#176920 Proteus syndrome P31749
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581

KEGG DISEASE (10)

KEGG name UniProt
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00015 Malignant pleural mesothelioma P08069 (related)
H00050 Synovial sarcoma P08069 (related)
H01274 Growth delay due to insulin-like growth factor I resistance P08069 (related)
H00018 Gastric cancer P08581 (related)
H00021 Renal cell carcinoma P08581 (related)
H00046 Cholangiocarcinoma P08581 (related)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00523 Noonan syndrome and related disorders Q02750 (related)
H00014 Non-small cell lung cancer Q9UM73 (related)