Swietenia mahagoni JACQ.
Species
KNApSAcK Entry
| Organism name | Swietenia mahagoni JACQ. |
|---|---|
| Genus | Swietenia |
| Family | Meliaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Swietenia |
|---|---|
| Linked NCBI taxonomy ID | 43890 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Meliaceae |
|---|---|
| ID | 43707 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (18)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00024090
|
3-O-Acetylswietenolide
|
CHEMBL1399553
CHEMBL2332200 |
6 / 14 / 42 | No. 102 |
|
|||
|
C00024091
|
6-O-Acetylswietenolide
|
No. 102 |
|
|||||
|
C00024107
|
Swietenin E
|
No. 102 |
|
|||||
|
C00024106
|
Swietenin D
|
No. 102 |
|
|||||
|
C00024105
|
Swietenin C
|
No. 102 |
|
|||||
|
C00024104
|
Swietenin B
|
No. 102 |
|
|||||
|
C00024108
|
Swietenin F
|
No. 102 |
|
|||||
|
C00024095
|
Secomahoganin
|
No. 204 | No. 51 |
|
||||
|
C00024093
|
Mahonin
|
No. 453 |
|
|||||
|
C00024103
|
Swietemahonolide
|
No. 535 |
|
|||||
|
C00024101
|
Swietemahonin F
|
No. 535 |
|
|||||
|
C00024102
|
Swietemahonin G
|
No. 535 |
|
|||||
|
C00024097
|
Swietemahonin B
|
No. 535 |
|
|||||
|
C00024096
|
Swietemahonin A
|
No. 535 |
|
|||||
|
C00024100
|
Swietemahonin E
|
No. 535 |
|
|||||
|
C00024099
|
Swietemahonin D
|
No. 535 |
|
|||||
|
C00024098
|
Swietemahonin C
|
No. 535 |
|
|||||
|
C00024092
|
Mahagonin
|
No. 8304 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00024090 | 7 / 37 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00024090 | 4 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00024090 | 2 / 3 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00024090 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00024090 | 0 / 1 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00024090 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (14)
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #133239 | Esophageal cancer |
P04637
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P04637
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (42)
| KEGG | name | UniProt |
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|