Swietenia macrophylla

• Index
• Plant Species
• Natural Activity
• Metabolite list (21)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Swietenia macrophylla
Genus	Swietenia
Family	Meliaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Swietenia macrophylla
Linked NCBI taxonomy ID	43891
Linked level	species

Family

Family in NCBI taxonomy	Meliaceae
ID	43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Natural Activity

List (9)

Species	Activity
Swietenia macrophylla King	Antifeedant
Swietenia macrophylla King	Astringent
Swietenia macrophylla King	Contraceptive
Swietenia macrophylla King	Depurative
Swietenia macrophylla King	Diuretic
Swietenia macrophylla King	Febrifuge
Swietenia macrophylla King	Hypotensive
Swietenia macrophylla King	Propecic
Swietenia macrophylla King	Tonic

Metabolite list (21)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00034297	Swietenolide					No. 102
C00048083	Roxburghiadiol A					No. 129	No. 11
C00048162	Swietenialide D					No. 196
C00048173	Swietenitin K / (+)-Swietenitin K					No. 196
C00048172	Swietenitin J					No. 196
C00048171	Swietenitin I / (-)-Swietenitin I					No. 196
C00048175	Swietenitin M					No. 196
C00048174	Swietenitin L					No. 196
C00048163	Swietenitin A / (-)-Swietenitin A					No. 196
C00048164	Swietenitin B / (+)-Swietenitin B					No. 196
C00048170	Swietenitin H					No. 196
C00048166	Swietenitin D / (-)-Swietenitin D					No. 196
C00048167	Swietenitin E / (-)-Swietenitin E					No. 196
C00048168	Swietenitin F / (-)-Swietenitin F					No. 196
C00048169	Swietenitin G / (-)-Swietenitin G					No. 196
C00048165	Swietenitin C / (-)-Swietenitin C					No. 196
C00024095	Secomahoganin					No. 204	No. 51
C00034777	7-Ketogedunin / 7-Deacetoxy-7-oxogedunin	CHEMBL374788 CHEMBL452232 CHEMBL1512460		6 / 13 / 43		No. 204	No. 51
C00038134	12alpha-Acetoxyswietephragmin C					No. 378
C00038135	12alpha-Acetoxyswietephragmin D					No. 378
C00038307	6-O-Acetylswietephragmin E					No. 378

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04637	Cellular tumor antigen p53	Transcription Factor	C00034777	7 / 37
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00034777	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00034777	2 / 3
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00034777	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00034777	0 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00034777	4 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions