Species

KNApSAcK Entry

Organism name Tabernaemontana apoda Wr.ex Sauv.
Genus Tabernaemontana
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tabernaemontana
Linked NCBI taxonomy ID 52860
Linked level genus

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025173 External link 512 Heyneanin
/ Heyneanine
/ (-)-Heyneanine
CHEMBL182405
CHEMBL361284
No. 250 No. 4
C00025223 External link 512 Voacangine
/ (-)-Voacangine
/ Carbomethoxyibogaine
CHEMBL182120
C012098
No. 250 No. 4
C00025916 External link 512 Isovoacangine
/ (-)-Isovoacangine
CHEMBL360427
CHEMBL1713663
5 / 3 / 1 No. 250 No. 4
C00025227 External link 512 Voacristine
/ (-)-Voacristine
/ (-)-Voacangarine
CHEMBL463317
CHEMBL512646
C049505
No. 250 No. 4
C00025225 External link 512 Voacangine pseudoindoxyl
No. 1434
C00025229 External link 512 Montanine
/ Voacristine pseudoindoxyl
/ Montanine(Tabernaemontana)
No. 1434
C00025228 External link 512 Voacristine hydroxyindolenine
/ Voacristine 7-hydroxyindolenine
/ Voacangarine 7-hydroxyindolenine
/ (19S)-Voacristine hydroxyindolenine
/ (20S)-Voacristine hydroxyindolenine
CHEMBL487613
CHEMBL460120
No. 1560
C00025224 External link 512 Voacangine hydroxyindolenine
/ 7alpha-Hydroxyvoacangine indolenine
CHEMBL488201
No. 1560
C00025891 External link 512 Ibogaine hydroxyindolenine
No. 3470

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00025916 2 / 0
O75496 Geminin Unclassified protein C00025916 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00025916 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00025916 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00025916 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
#613795 Loeys-dietz syndrome, type 3; lds3 P84022

KEGG DISEASE (1)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)