Species

KNApSAcK Entry

Organism name Streptomyces laurentii
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces laurentii
Linked NCBI taxonomy ID 39478
Linked level species

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000753 External link 512 Thiostrepton
CHEMBL410968
CHEMBL468719
CHEMBL1981887
CHEMBL2303629
D013883
6 / 8 / 4 No. 2544

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00000753 4 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00000753 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00000753 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00000753 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000753 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00000753 4 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (4)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)