Organism name | Salvia drobovii |
---|---|
Genus | Salvia |
Family | Labiatae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Salvia |
---|---|
Linked NCBI taxonomy ID | 21880 |
Linked level | genus |
Family in NCBI taxonomy | Lamiaceae |
---|---|
ID | 4136 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | asterids |
---|---|
ID | 71274 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00037506
![]() |
Miltirone
|
CHEMBL45830
|
C068880
|
6 / 1 / 0 | No. 3136 |
![]() |
||
C00031697
![]() |
Cryptotanshinone
|
CHEMBL187460
CHEMBL1518673 |
C037886
|
45 / 36 / 34 | 7 / 0 | No. 5489 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
O00748 | Cocaine esterase | Enzyme | C00031697 C00037506 | 0 / 0 |
P23141 | Liver carboxylesterase 1 | Enzyme | C00031697 C00037506 | 0 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00031697 C00037506 | 1 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00031697 | 2 / 2 |
P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00037506 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00031697 | 3 / 1 |
P54132 | Bloom syndrome protein | Enzyme | C00031697 | 1 / 2 |
Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00031697 | 1 / 0 |
P11473 | Vitamin D3 receptor | NR1I1 | C00031697 | 2 / 3 |
O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00031697 | 0 / 0 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00031697 | 0 / 0 |
P39748 | Flap endonuclease 1 | Enzyme | C00031697 | 0 / 0 |
Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00031697 | 0 / 0 |
P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00031697 | 2 / 0 |
O75496 | Geminin | Unclassified protein | C00031697 | 0 / 0 |
P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00031697 | 1 / 2 |
P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00031697 | 0 / 0 |
Q9Y253 | DNA polymerase eta | Enzyme | C00031697 | 1 / 1 |
Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00031697 | 0 / 0 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00031697 | 1 / 2 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00031697 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00031697 | 0 / 0 |
P30304 | M-phase inducer phosphatase 1 | Ser_Thr_Tyr | C00037506 | 0 / 0 |
Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00031697 | 3 / 3 |
P06746 | DNA polymerase beta | Enzyme | C00031697 | 0 / 0 |
Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00031697 | 0 / 0 |
P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00031697 | 2 / 0 |
P30305 | M-phase inducer phosphatase 2 | Ser_Thr_Tyr | C00037506 | 0 / 0 |
P55210 | Caspase-7 | C14 | C00031697 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00031697 | 0 / 1 |
Q9UNA4 | DNA polymerase iota | Enzyme | C00031697 | 0 / 0 |
Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00031697 | 1 / 0 |
O75164 | Lysine-specific demethylase 4A | Enzyme | C00031697 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00031697 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00031697 | 4 / 3 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00031697 | 0 / 0 |
Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00031697 | 0 / 0 |
O14746 | Telomerase reverse transcriptase | Enzyme | C00031697 | 5 / 5 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00031697 | 0 / 0 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00031697 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00031697 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00031697 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00031697 | 1 / 1 |
O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00031697 | 1 / 0 |
O00255 | Menin | Unclassified protein | C00031697 | 2 / 5 |
Q13951 | Core-binding factor subunit beta | Unclassified protein | C00031697 | 0 / 1 |
Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00031697 | 1 / 4 |
Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00031697 | 2 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
43 | ACHE, ACEE, ARACHE, N-ACHE, YT | acetylcholinesterase (EC:3.1.1.7) |
C00031697
|
196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00031697
|
590 | BCHE, CHE1, CHE2, E1 | butyrylcholinesterase (EC:3.1.1.8) |
C00031697
|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00031697
|
1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00031697
|
1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00031697
|
8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00031697
|
OMIM | preferred title | UniProt |
---|---|---|
#300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
#609135 | Aplastic anemia |
O14746
|
#608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
#210900 | Bloom syndrome; blm |
P54132
|
#114500 | Colorectal cancer; crc |
P84022
Q14191 |
#119900 | Digital clubbing, isolated congenital |
P15428
|
#613989 | Dyskeratosis congenita, autosomal dominant, 2; dkca2 |
O14746
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#137800 | Glioma susceptibility 1; glm1 |
O75874
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
#615134 | Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 |
O14746
|
#300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
#300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
#614742 | Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 |
O14746
|
#178500 | Pulmonary fibrosis, idiopathic; ipf |
O14746
|
#604906 | Schizophrenia 9; sczd9 |
P49798
|
#181500 | Schizophrenia; sczd |
P49798
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
#277700 | Werner syndrome; wrn |
Q14191
|
#278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00764 | Cri du chat syndrome |
O14746
(related)
|
H01132 | Aplastic anemia (AA) |
O14746
(related)
|
H01299 | Idiopathic pulmonary fibrosis |
O14746
(related)
|
H00022 | Bladder cancer |
O14746
(marker)
|
H00024 | Prostate cancer |
O14746
(marker)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00016 | Oral cancer |
P40763
(related)
|
H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
H00094 | DNA repair defects |
P54132
(related)
|
H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|