Species

KNApSAcK Entry

Organism name Colubrina granulosa
Genus Colubrina
Family Rhamnaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Colubrina
Linked NCBI taxonomy ID 106663
Linked level genus

Family

Family in NCBI taxonomy Rhamnaceae
ID 3608

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00032552 External link 512 Colubrinic acid
/ Zizyberanalic acid
CHEMBL470503
CHEMBL1503007
CHEMBL1782597
13 / 10 / 9 No. 23 No. 51

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00032552 1 / 1
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00032552 1 / 4
P08151 Zinc finger protein GLI1 Unclassified protein C00032552 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00032552 2 / 0
O75496 Geminin Unclassified protein C00032552 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00032552 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00032552 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00032552 0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00032552 1 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00032552 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00032552 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00032552 0 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00032552 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#208900 Ataxia-telangiectasia; at Q13315
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (9)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)