Aglaia gracilis
Species
KNApSAcK Entry
| Organism name | Aglaia gracilis |
|---|---|
| Genus | Aglaia |
| Family | Meliaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Aglaia |
|---|---|
| Linked NCBI taxonomy ID | 201006 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Meliaceae |
|---|---|
| ID | 43707 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (10)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00036691
|
Aglafoline
/ (-)-Aglafoline |
CHEMBL394528
CHEMBL583849 CHEMBL1475040 |
C077355
|
8 / 2 / 3 | No. 449 |
|
||
|
C00034250
|
Shoreic acid
|
CHEMBL479139
CHEMBL479140 |
No. 827 |
|
||||
|
C00033260
|
Odorine
|
CHEMBL521297
CHEMBL483419 |
4 / 7 / 37 | No. 1008 |
|
|||
|
C00037655
|
Piriferine
/ (+)-Piriferine |
CHEMBL483215
CHEMBL1358178 CHEMBL1741443 CHEMBL1901093 |
5 / 2 / 3 | No. 1008 |
|
|||
|
C00037802
|
Secoodorine
|
No. 1515 |
|
|||||
|
C00037803
|
Secopiriferine
|
No. 1515 |
|
|||||
|
C00036414
|
13-Hydroxy-7-oxo-labda-8,14-diene
|
No. 2925 |
|
|||||
|
C00034182
|
Pyramidatine
|
CHEMBL483414
|
No. 2973 |
|
||||
|
C00036692
|
Aglaroxin D
/ Aglaiastatin / (+)-Aglaroxin D |
CHEMBL513658
|
No. 5806 |
|
||||
|
C00037476
|
Marikarin
/ (-)-Marikarin |
No. 6286 |
|
Human Protein / Gene in interactions
12 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00036691 C00037655 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00036691 C00037655 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00036691 C00037655 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00036691 C00037655 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00036691 C00037655 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00033260 | 0 / 0 |
| Q04206 | Transcription factor p65 | Transcription Factor | C00036691 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00036691 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00033260 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00033260 | 7 / 37 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00033260 | 0 / 0 |
| P60842 | Eukaryotic initiation factor 4A-I | Enzyme | C00036691 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #133239 | Esophageal cancer |
P04637
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #211980 | Lung cancer |
P04637
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
KEGG DISEASE (39)
| KEGG | name | UniProt |
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|