PCIDB

Ferula loscosii

Species

KNApSAcK Entry

Organism name Ferula loscosii
Genus Ferula
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ferula loscosii
Linked NCBI taxonomy ID 371365
Linked level species

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00034468 External link 512 Coladin
No. 209
C00034469 External link 512 Coladonin
CHEMBL178485
CHEMBL1078138
CHEMBL1326960
CHEMBL1507262
CHEMBL2000585
13 / 14 / 10 No. 209
C00034737 External link 512 Umbelliprenin
CHEMBL156127
8 / 3 / 3 No. 2038

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75496 Geminin Unclassified protein C00034469 C00034737 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00034469 C00034737 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00034469 0 / 0
P37840 Alpha-synuclein Unclassified protein C00034469 4 / 2
P16473 Thyrotropin receptor Glycohormone receptor C00034469 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00034469 0 / 1
P17405 Sphingomyelin phosphodiesterase Enzyme C00034737 2 / 2
P39748 Flap endonuclease 1 Enzyme C00034737 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00034469 2 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00034469 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00034469 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00034737 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00034469 3 / 3
P16050 Arachidonate 15-lipoxygenase Enzyme C00034737 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00034469 1 / 1
Q99700 Ataxin-2 Unclassified protein C00034469 1 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00034737 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00034469 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00034737 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#114500 Colorectal cancer; crc P84022
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8

KEGG DISEASE (12)

KEGG name UniProt
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)