Species

KNApSAcK Entry

Organism name Aglaia basiphylla
Genus Aglaia
Family Meliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aglaia basiphylla
Linked NCBI taxonomy ID 306494
Linked level species

Family

Family in NCBI taxonomy Meliaceae
ID 43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036691 External link 512 Aglafoline
/ (-)-Aglafoline
CHEMBL394528
CHEMBL583849
CHEMBL1475040
C077355
8 / 2 / 3 No. 449
C00037744 External link 512 Rocaglamide
CHEMBL438139
CHEMBL601614
C107772
9 / 7 / 7 No. 449

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q04206 Transcription factor p65 Transcription Factor C00036691 C00037744 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00037744 0 / 0
P37840 Alpha-synuclein Unclassified protein C00037744 4 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00036691 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00036691 0 / 0
O75496 Geminin Unclassified protein C00037744 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00036691 1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00036691 0 / 0
Q99700 Ataxin-2 Unclassified protein C00037744 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00036691 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00036691 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00037744 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00037744 1 / 0
P60842 Eukaryotic initiation factor 4A-I Enzyme C00036691 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00037744 0 / 3
Q13148 TAR DNA-binding protein 43 Unclassified protein C00037744 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137800 Glioma susceptibility 1; glm1 O75874
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (10)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)