Species

KNApSAcK Entry

Organism name Nothofagus fusca
Genus Nothofagus
Family Nothofagaceae / Fagaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Nothofagus fusca
Linked NCBI taxonomy ID 28941
Linked level species

Family

Family in NCBI taxonomy Nothofagaceae
ID 26778

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000937 External link 512 Afzelechin
CHEMBL159303
CHEMBL1326092
7 / 4 / 12 No. 52 No. 14
C00014024 External link 512 Nothofagin
/ 1-(3-beta-D-Glucopyranosyl-2,4,6-trihydroxyphenyl)-3-(4-hydroxyphenyl)-1-propanone
No. 261 No. 14

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00000937 0 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00000937 0 / 0
Q9UM73 ALK tyrosine kinase receptor TKL serine/threonine protein kinase STKR type 1 subfamily C00000937 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000937 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00000937 0 / 0
O00255 Menin Unclassified protein C00000937 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00000937 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613014 Neuroblastoma, susceptibility to, 3; nblst3 Q9UM73

KEGG DISEASE (12)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00014 Non-small cell lung cancer Q9UM73 (related)