| Organism name | Karenia brevis |
|---|---|
| Genus | |
| Family | |
| Kingdom |
| Linked NCBI taxonomy name | Karenia brevis |
|---|---|
| Linked NCBI taxonomy ID | 156230 |
| Linked level | species |
| Family in NCBI taxonomy | Kareniaceae |
|---|---|
| ID | 1003176 |
| Kingdom (Superkingdom) in NCBI taxonomy | Eukaryota |
|---|---|
| ID | 2759 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00042300
|
Brevetoxin A
|
CHEMBL1448627
CHEMBL2152260 |
C076262
|
18 / 15 / 16 | No. 2725 |
|
||
|
C00042301
|
Brevetoxin B
|
CHEMBL216458
CHEMBL413858 |
C043466
|
3 / 5 / 4 | 1 / 0 | No. 2725 |
|
|
|
C00048634
|
Brevisamide
|
No. 5856 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00042300 | 1 / 1 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00042300 | 1 / 4 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00042300 | 2 / 3 |
| P42858 | Huntingtin | Unclassified protein | C00042300 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00042300 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00042300 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00042300 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00042300 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00042300 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00042300 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00042300 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00042300 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00042300 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00042300 | 1 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00042300 | 4 / 3 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00042300 | 1 / 0 |
| Q9NY46 | Sodium channel protein type 3 subunit alpha | SCN alpha, NaV1.x | C00042301 | 0 / 0 |
| Q99250 | Sodium channel protein type 2 subunit alpha | SCN alpha, NaV1.x | C00042301 | 2 / 2 |
| P35498 | Sodium channel protein type 1 subunit alpha | SCN alpha, NaV1.x | C00042301 | 3 / 2 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00042300 | 0 / 3 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00042300 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00042301
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #607208 | Dravet syndrome |
P35498
|
| #613721 | Epileptic encephalopathy, early infantile, 11; eiee11 |
Q99250
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #604403 | Generalized epilepsy with febrile seizures plus, type 2; gefsp2 |
P35498
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #143100 | Huntington disease; hd |
P42858
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #609634 | Migraine, familial hemiplegic, 3; fhm3 |
P35498
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #607745 | Seizures, benign familial infantile, 3; bfis3 |
Q99250
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00775 | Familial or sporadic hemiplegic migraine |
P35498
(related)
|
| H00783 | Febrile seizures |
P35498
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00606 | Early infantile epileptic encephalopathy |
Q99250
(related)
|
| H00806 | Benign familial neonatal and infantile epilepsies |
Q99250
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|