Entandrophragma angolense

• Index
• Plant Species
• Metabolite list (1)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Entandrophragma angolense
Genus	Entandrophragma
Family	Meliaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Entandrophragma angolense
Linked NCBI taxonomy ID	587577
Linked level	species

Family

Family in NCBI taxonomy	Meliaceae
ID	43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (1)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00047901	Gedunin	CHEMBL465226 CHEMBL1335340 CHEMBL2004035	C106014	16 / 33 / 55	83 / 1	No. 204	No. 51

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04637	Cellular tumor antigen p53	Transcription Factor	C00047901	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00047901	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00047901	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00047901	11 / 10
P11473	Vitamin D3 receptor	NR1I1	C00047901	2 / 3
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00047901	2 / 0
O75496	Geminin	Unclassified protein	C00047901	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00047901	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00047901	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00047901	0 / 0
P08238	Heat shock protein HSP 90-beta	Other cytosolic protein	C00047901	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00047901	0 / 1
Q6W5P4	Neuropeptide S receptor	Neuropeptide receptor	C00047901	1 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00047901	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00047901	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00047901	1 / 0

83 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
10598	AHSA1, AHA1, C14orf3, p38	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	C00047901
1645	AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB	aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112)	C00047901
1646	AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8	aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357)	C00047901
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00047901
84159	ARID5B, DESRT, MRF-2, MRF2	AT rich interactive domain 5B (MRF1-like)	C00047901
467	ATF3	activating transcription factor 3	C00047901
9531	BAG3, BAG-3, BIS, CAIR-1, MFM6	BCL2-associated athanogene 3	C00047901
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00047901
694	BTG1	B-cell translocation gene 1, anti-proliferative	C00047901
8209	C21orf33, ES1, GT335, HES1, KNPH, KNPI	chromosome 21 open reading frame 33	C00047901
27101	CACYBP, GIG5, RP1-102G20.6, S100A6BP, SIP	calcyclin binding protein	C00047901
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00047901
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00047901
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00047901
874	CBR3, SDR21C2, hCBR3	carbonyl reductase 3 (EC:1.1.1.184)	C00047901
8317	CDC7, CDC7L1, HsCDC7, Hsk1, huCDC7	cell division cycle 7 (EC:2.7.11.1)	C00047901
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00047901
26973	CHORDC1, CHP1	cysteine and histidine-rich domain (CHORD) containing 1	C00047901
10370	CITED2, ASD8, MRG-1, MRG1, P35SRJ, VSD2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	C00047901
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00047901
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00047901
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00047901
3301	DNAJA1, DJ-2, DjA1, HDJ2, HSDJ, HSJ2, HSPF4, NEDD7, hDJ-2	DnaJ (Hsp40) homolog, subfamily A, member 1	C00047901
11080	DNAJB4, DNAJW, DjB4, HLJ1	DnaJ (Hsp40) homolog, subfamily B, member 4	C00047901
1948	EFNB2, EPLG5, HTKL, Htk-L, LERK5	ephrin-B2	C00047901
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00047901
11153	FICD, HIP13, HYPE, UNQ3041	FIC domain containing (EC:2.7.7.n1)	C00047901
2322	FLT3, CD135, FLK-2, FLK2, STK1	fms-related tyrosine kinase 3 (EC:2.7.10.1)	C00047901
2730	GCLM, GLCLR	glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2)	C00047901
9518	GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB	growth differentiation factor 15	C00047901
54676	GTPBP2	GTP binding protein 2	C00047901
29923	HILPDA, C7orf68, HIG-2, HIG2	hypoxia inducible lipid droplet-associated	C00047901
3157	HMGCS1, HMGCS	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10)	C00047901
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00047901
3320	HSP90AA1, EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	C00047901
3303	HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1	heat shock 70kDa protein 1A	C00047901
3304	HSPA1B, HSP70-1B, HSP70-2	heat shock 70kDa protein 1B	C00047901
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00047901
10808	HSPH1, HSP105, HSP105A, HSP105B, NY-CO-25	heat shock 105kDa/110kDa protein 1	C00047901
3557	IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4	interleukin 1 receptor antagonist	C00047901
3638	INSIG1, CL-6, CL6	insulin induced gene 1	C00047901
182	JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1	jagged 1	C00047901
3781	KCNN2, KCa2.2, SK2, SKCA2, SKCa_2, hSK2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	C00047901
3949	LDLR, FH, FHC, LDLCQ2	low density lipoprotein receptor	C00047901
23175	LPIN1, PAP1	lipin 1 (EC:3.1.3.4)	C00047901
26046	LTN1, C21orf10, C21orf98, RNF160, ZNF294	listerin E3 ubiquitin protein ligase 1	C00047901
9935	MAFB, KRML, MCTO	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B	C00047901
4191	MDH2, M-MDH, MDH, MGC:3559, MOR1	malate dehydrogenase 2, NAD (mitochondrial) (EC:1.1.1.37)	C00047901
4199	ME1, HUMNDME, MES	malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40)	C00047901
4335	MNT, MAD6, MXD6, ROX, bHLHd3	MAX network transcriptional repressor	C00047901
29074	MRPL18, L18mt, MRP-L18	mitochondrial ribosomal protein L18	C00047901
2956	MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160	mutS homolog 6	C00047901
6307	MSMO1, DESP4, ERG25, SC4MOL	methylsterol monooxygenase 1 (EC:1.14.13.72)	C00047901
23077	MYCBP2, PAM	MYC binding protein 2, E3 ubiquitin protein ligase	C00047901
55892	MYNN, OSZF, ZBTB31, ZNF902	myoneurin	C00047901
4683	NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95	nibrin	C00047901
4824	NKX3-1, BAPX2, NKX3, NKX3.1, NKX3A	NK3 homeobox 1	C00047901
9315	NREP, C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17	neuronal regeneration related protein	C00047901
4986	OPRK1, K-OR-1, KOR, KOR-1, OPRK	opioid receptor, kappa 1	C00047901
51526	OSER1, C20orf111, HSPC207, Osr1, Perit1, dJ1183I21.1	oxidative stress responsive serine-rich 1	C00047901
5152	PDE9A, HSPDE9A2	phosphodiesterase 9A (EC:3.1.4.35)	C00047901
5293	PIK3CD, P110DELTA, PI3K, p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153)	C00047901
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00047901
10105	PPIF, CYP3, CyP-M, Cyp-D, CypD	peptidylprolyl isomerase F (EC:5.2.1.8)	C00047901
5813	PURA, PUR-ALPHA, PUR1, PURALPHA	purine-rich element binding protein A	C00047901
6241	RRM2, R2, RR2, RR2M	ribonucleotide reductase M2 (EC:1.17.4.1)	C00047901
27230	SERP1, RAMP4	stress-associated endoplasmic reticulum protein 1	C00047901
27244	SESN1, PA26, SEST1	sestrin 1	C00047901
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00047901
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00047901
79811	SLTM, Met	SAFB-like, transcription modulator	C00047901
6659	SOX4, EVI16	SRY (sex determining region Y)-box 4	C00047901
100380807			C00047901
10963	STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L	stress-induced-phosphoprotein 1	C00047901
51347	TAOK3, DPK, JIK, MAP3K18	TAO kinase 3 (EC:2.7.11.1)	C00047901
7113	TMPRSS2, PP9284, PRSS10	transmembrane protease, serine 2 (EC:3.4.21.-)	C00047901
10628	TXNIP, EST01027, HHCPA78, THIF, VDUP1	thioredoxin interacting protein	C00047901
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00047901
7320	UBE2B, E2-17kDa, HHR6B, HR6B, RAD6B, UBC2	ubiquitin-conjugating enzyme E2B (EC:6.3.2.19)	C00047901
7358	UGDH, GDH, UDP-GlcDH, UDPGDH, UGD	UDP-glucose 6-dehydrogenase (EC:1.1.1.22)	C00047901
79084	WDR77, MEP-50, MEP50, Nbla10071, RP11-552M11.3, p44, p44/Mep50	WD repeat domain 77	C00047901
23099	ZBTB43, ZBTB22B, ZNF-X, ZNF297B	zinc finger and BTB domain containing 43	C00047901
80149	ZC3H12A, MCPIP, MCPIP1, RP3-423B22.1, dJ423B22.1	zinc finger CCCH-type containing 12A	C00047901

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions