Species

KNApSAcK Entry

Organism name Melia indica
Genus Melia
Family Meliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Melia
Linked NCBI taxonomy ID 43708
Linked level genus

Family

Family in NCBI taxonomy Meliaceae
ID 43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00049007 External link 512 Nimbolide
CHEMBL426690
CHEMBL1968854
C042198
20 / 1 No. 2762

Human Protein / Gene in interactions

20 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
317 APAF1, APAF-1, CED4 apoptotic peptidase activating factor 1 C00049007
572 BAD, BBC2, BCL2L8 BCL2-associated agonist of cell death C00049007
581 BAX, BCL2L4 BCL2-associated X protein C00049007
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00049007
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00049007
637 BID, FP497 BH3 interacting domain death agonist C00049007
332 BIRC5, API4, EPR-1 baculoviral IAP repeat containing 5 C00049007
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00049007
839 CASP6, MCH2 caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) C00049007
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00049007
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00049007
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00049007
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00049007
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00049007
3551 IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) C00049007
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00049007
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00049007
5111 PCNA proliferating cell nuclear antigen C00049007
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00049007
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00049007

Related Diseases

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009369 Neoplasms C00049007