Species

KNApSAcK Entry

Organism name Ceterach officinarum
Genus Ceterach
Family Aspleniaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Asplenium ceterach
Linked NCBI taxonomy ID 147945
Linked level species

Family

Family in NCBI taxonomy Aspleniaceae
ID 41972

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Euphyllophyta
ID 78536

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005411 External link 512 Quercetin 3-gentiobioside
CHEMBL1097317
C088177
No. 1 No. 15
C00005840 External link 512 Kaempferol 3-(6''-malonylgalactoside)
No. 2 No. 15
C00005844 External link 512 Kaempferol 3-(6''-malonylglucoside)
No. 2 No. 15
C00000983 External link 512 Naringin
CHEMBL451532
CHEMBL451512
CHEMBL1742953
CHEMBL1970019
C005274
18 / 12 / 6 12 / 4 No. 48 No. 14
C00008215 External link 512 5,7,4'-Trihydroxyflavanone 7-O-arabinosylglucoside
No. 48 No. 14

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00000983 3 / 0
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00000983 0 / 0
Q9Y6L6 Solute carrier organic anion transporter family member 1B1 Electrochemical transporter C00000983 1 / 0
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00000983 0 / 0
P08183 Multidrug resistance protein 1 drug C00000983 1 / 0
O75496 Geminin Unclassified protein C00000983 0 / 0
P46721 Solute carrier organic anion transporter family member 1A2 Unclassified protein C00000983 0 / 0
P54855 UDP-glucuronosyltransferase 2B15 Enzyme C00000983 0 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00000983 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00000983 0 / 0
Q9NPD5 Solute carrier organic anion transporter family member 1B3 Electrochemical transporter C00000983 1 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00000983 2 / 2
P61088 Ubiquitin-conjugating enzyme E2 N Enzyme C00000983 0 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00000983 5 / 1
Q9Y251 Heparanase Enzyme C00000983 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000983 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00000983 1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00000983 1 / 1

12 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00000983
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000983
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00000983
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00000983
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00000983
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000983
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00000983
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00000983
8772 FADD, MORT1 Fas (TNFRSF6)-associated via death domain C00000983
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00000983
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00000983
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00000983

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#612219 Ewing sarcoma; es P11308
#143500 Gilbert syndrome P22309
P22310
#137800 Glioma susceptibility 1; glm1 O75874
#237450 Hyperbilirubinemia, rotor type; hblrr Q9NPD5
Q9Y6L6
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#612244 Inflammatory bowel disease 13; ibd13 P08183

KEGG DISEASE (6)

KEGG name UniProt
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)

Diseases related to CTD interactions

4 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D058186 Acute Kidney Injury C00000983
D056486 Drug-Induced Liver Injury C00000983
D009203 Myocardial Infarction C00000983
D002583 Uterine Cervical Neoplasms C00000983