| Organism name | Evodiopanax spp. | 
|---|---|
| Genus | Evodiopanax | 
| Family | Araliaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Gamblea | 
|---|---|
| Linked NCBI taxonomy ID | 127422 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Araliaceae | 
|---|---|
| ID | 4050 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00000983   | Naringin | CHEMBL451532 CHEMBL451512 CHEMBL1742953 CHEMBL1970019 | C005274 | 18 / 12 / 6 | 12 / 4 | No. 48 | No. 14 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00000983 | 3 / 0 | 
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00000983 | 0 / 0 | 
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00000983 | 1 / 0 | 
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00000983 | 0 / 0 | 
| P08183 | Multidrug resistance protein 1 | drug | C00000983 | 1 / 0 | 
| O75496 | Geminin | Unclassified protein | C00000983 | 0 / 0 | 
| P46721 | Solute carrier organic anion transporter family member 1A2 | Unclassified protein | C00000983 | 0 / 0 | 
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00000983 | 0 / 0 | 
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00000983 | 1 / 2 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000983 | 0 / 0 | 
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00000983 | 1 / 0 | 
| P11511 | Cytochrome P450 19A1 | Cytochrome P450 19A1 | C00000983 | 2 / 2 | 
| P61088 | Ubiquitin-conjugating enzyme E2 N | Enzyme | C00000983 | 0 / 0 | 
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00000983 | 5 / 1 | 
| Q9Y251 | Heparanase | Enzyme | C00000983 | 0 / 0 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000983 | 0 / 0 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000983 | 1 / 0 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000983 | 1 / 1 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00000983 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00000983 | 
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) | C00000983 | 
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) | C00000983 | 
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) | C00000983 | 
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) | C00000983 | 
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) | C00000983 | 
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) | C00000983 | 
| 8772 | FADD, MORT1 | Fas (TNFRSF6)-associated via death domain | C00000983 | 
| 355 | FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 | Fas cell surface death receptor | C00000983 | 
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 | C00000983 | 
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 | C00000983 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | Q13148 | 
| #613546 | Aromatase deficiency | P11511 | 
| #139300 | Aromatase excess syndrome; aexs | P11511 | 
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 | P22309 | 
| #218800 | Crigler-najjar syndrome, type i | P22309 P22310 | 
| #606785 | Crigler-najjar syndrome, type ii | P22309 P22310 | 
| #612219 | Ewing sarcoma; es | P11308 | 
| #143500 | Gilbert syndrome | P22309 P22310 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #237450 | Hyperbilirubinemia, rotor type; hblrr | Q9NPD5 Q9Y6L6 | 
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn | P22309 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00024 | Prostate cancer | P11308
                            (related) | 
| H00035 | Ewing's sarcoma | P11308
                            (related) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P11511
                            (related) | 
| H00794 | Aromatase excess syndrome | P11511
                            (related) | 
| H00208 | Hyperbilirubinemia | P22309
                            (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | Q13148
                            (related) |