Arnica spp.

• Index
• Plant Species
• Metabolite list (8)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Arnica spp.
Genus	Arnica
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Arnica
Linked NCBI taxonomy ID	4246
Linked level	genus

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (8)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005955	Quercetin 3-(6''-acetylglucoside) / Quercetin 3-O-2G-rhamnosylrutinoside	CHEMBL250695 CHEMBL559041				No. 2	No. 15
C00005641	Patuletin 3-glucuronide					No. 2	No. 15
C00005527	Isorhamnetin 3-glucuronide					No. 2	No. 15
C00004689	Spinacetin / Quercetagetin 3',6-dimethyl ether / 3,4',5,7-Tetrahydroxy-3',6-dimethoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one					No. 3	No. 15
C00004680	Patuletin / 6-Methoxyquercetin / 3,5,7,3',4'-Pentahydroxy-6-methoxyflavone / 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-6-methoxy-4H-1-benzopyran-4-one	CHEMBL465155	C079162			No. 3	No. 15
C00004635	Isorhamnetin / 3'-O-Methylquercetin / 3,4',5,7-Tetrahydroxy-3'-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one	CHEMBL379064	C047368	12 / 10 / 13	10 / 0	No. 3	No. 15
C00004600	3,5,7-Trihydroxy-6,4'-dimethoxyflavone / 6,4'-Dimethoxy-3,5,7-trihydroxyflavone	CHEMBL311155				No. 3	No. 15
C00001036	Diosmetin / 4'-Methylluteolin / 5,7,3'-Trihydroxy-4'-methoxyflavone	CHEMBL90568	C039602	11 / 12 / 8	5 / 0	No. 3	No. 15

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P04745	Alpha-amylase 1	Enzyme	C00001036 C00004635	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001036 C00004635	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001036 C00004635	0 / 0
Q16678	Cytochrome P450 1B1	Cytochrome P450 1B1	C00001036 C00004635	4 / 4
P04798	Cytochrome P450 1A1	Cytochrome P450 1A1	C00001036 C00004635	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00001036	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00004635	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00001036	5 / 3
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00004635	1 / 1
P04792	Heat shock protein beta-1	Unclassified protein	C00004635	2 / 1
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00001036	0 / 0
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00001036	2 / 0
Q92887	Canalicular multispecific organic anion transporter 1	Unclassified protein	C00001036	1 / 1
P09917	Arachidonate 5-lipoxygenase	Oxidoreductase	C00004635	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00001036	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00004635	0 / 0
O00255	Menin	Unclassified protein	C00004635	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00004635	1 / 2

12 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00001036 C00004635
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00001036 C00004635
1545	CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1	cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001036 C00004635
196	AHR, bHLHe76	aryl hydrocarbon receptor	C00004635
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00001036
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00004635
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00001036
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00004635
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00004635
4846	NOS3, ECNOS, eNOS	nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39)	C00004635
4973	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1	oxidized low density lipoprotein (lectin-like) receptor 1	C00004635
7031	TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2	trefoil factor 1	C00004635

Related Diseases

Diseases related to proteins in ChEMBL interactions