Species

KNApSAcK Entry

Organism name Brickellia laciniata
Genus Brickellia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Brickellia
Linked NCBI taxonomy ID 102753
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001036 External link 512 Diosmetin
/ 4'-Methylluteolin
/ 5,7,3'-Trihydroxy-4'-methoxyflavone
CHEMBL90568
C039602
11 / 12 / 8 5 / 0 No. 3 No. 15
C00004690 External link 512 Laciniatin
/ 3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
No. 3 No. 15
C00023294 External link 512 2alpha-Hydroxy-7-labden-15-oic acid
No. 393
C00011420 External link 512 Brickelliol
/ (E,E)-3,7,11,-Trimethyl-1,4,6,10-tetraen-3-ol
No. 4429

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs C00001036 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00001036 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001036 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00001036 5 / 3
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001036 4 / 4
P04745 Alpha-amylase 1 Enzyme C00001036 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001036 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001036 2 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00001036 1 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001036 0 / 0
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00001036 0 / 0

5 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00001036
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001036
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001036
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00001036
1577 CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) C00001036

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#237500 Dubin-johnson syndrome; djs Q92887
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231
#604229 Peters anomaly Q16678
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (8)

KEGG name UniProt
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)
H00208 Hyperbilirubinemia Q92887 (related)