PCIDB

Lepidium sativum

Species

KNApSAcK Entry

Organism name Lepidium sativum
Genus Lepidium
Family Cruciferae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lepidium sativum
Linked NCBI taxonomy ID 33125
Linked level species

Family

Family in NCBI taxonomy Brassicaceae
ID 3700

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (19)

Species Activity
Lepidium sativum L. Abortifacient
Lepidium sativum L. Antibacterial
Lepidium sativum L. Antidote
Lepidium sativum L. Antiencephalic
Lepidium sativum L. Antiscorbuti
Lepidium sativum L. Antiviral
Lepidium sativum L. Aperitif
Lepidium sativum L. Aphrodisiac
Lepidium sativum L. Depurative
Lepidium sativum L. Diuretic
Lepidium sativum L. Emmenagogue
Lepidium sativum L. Enteroprotective
Lepidium sativum L. Gastroprotective
Lepidium sativum L. Immunostimulant
Lepidium sativum L. Lactagogue
Lepidium sativum L. Laxative
Lepidium sativum L. Piscicide
Lepidium sativum L. Stimulant
Lepidium sativum L. Stomachic

Metabolite list (20)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00007355 External link 512 Glucohirsutin
/ 8-Methylsulfinyloctyl glucosinolate
No. 46 No. 76
C00007864 External link 512 Epiprogoitrin
/ 2(S)-2-Hydroxy-3-butenyl glucosinolate
No. 46 No. 76
C00001488 External link 512 Sinigrin
/ Allyl glucosinolate
/ 2-Phenylethyl glucosinolate
No. 46 No. 76
C00001474 External link 512 Glucolepidiin
/ Ethyl glucosinolate
No. 46 No. 76
C00001486 External link 512 Progoitrin
/ 2(R)-2-Hydroxy 3-butenyl glucosinolate
C009048
No. 46 No. 76
C00000125 External link 512 Glucobrassicin
/ Glucobrassicine
/ 3-Indolylmethylglucosinolate
C048308
2 / 0 No. 158 No. 77
C00007805 External link 512 Glucosinalbate
/ 4-Hydroxybenzyl glucosinolate
No. 158 No. 77
C00000126 External link 512 Neoglucobrassicin
/ 1-Methoxy-3-indolylmethylglucosinolate
C064701
2 / 0 No. 158 No. 77
C00007346 External link 512 Tropaeolin
/ Glucotropaeolin
/ Benzylglucosinolate
C060321
No. 158 No. 77
C00007350 External link 512 Gluconasturtiin
/ 2-Phenylethylglucosinolate
C443697
No. 158 No. 77
C00002776 External link 512 Sinapic acid
CHEMBL109341
C073734
5 / 5 / 5 0 / 5 No. 1366 No. 6
C00028987 External link 512 Semilepidinoside A
No. 2078
C00028988 External link 512 Semilepidinoside B
No. 2078
C00028459 External link 512 Lepidine B
No. 2273
C00028460 External link 512 Lepidine C
No. 2273
C00028461 External link 512 Lepidine D
No. 2273
C00028463 External link 512 Lepidine F
No. 2273
C00028462 External link 512 Lepidine E
No. 2273
C00002777 External link 512 Sinapine
/ Sinapoylcholine
C005685
No. 2905 No. 6
C00001138 External link 512 Lepidimoide
C103036
No. 5149

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002776 0 / 3
Q13093 Platelet-activating factor acetylhydrolase Enzyme C00002776 3 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00002776 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00002776 2 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002776 0 / 0

4 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
2877 GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9) C00000125
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00000125
3251 HPRT1, HGPRT, HPRT hypoxanthine phosphoribosyltransferase 1 (EC:2.4.2.8) C00000126
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00000126

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#600807 Asthma, susceptibility to Q13093
#147050 Ige responsiveness, atopic; iger Q13093
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#614278 Platelet-activating factor acetylhydrolase deficiency; pafad Q13093

KEGG DISEASE (5)

KEGG name UniProt
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00002776
D000860 Anoxia C00002776
D001930 Brain Injuries C00002776
D056486 Drug-Induced Liver Injury C00002776
D004487 Edema C00002776