Species

KNApSAcK Entry

Organism name Nothofagus menziesii
Genus Nothofagus
Family Nothofagaceae / Fagaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Nothofagus menziesii
Linked NCBI taxonomy ID 28945
Linked level species

Family

Family in NCBI taxonomy Nothofagaceae
ID 26778

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001060 External link 512 Kaempferide
CHEMBL40919
6 / 7 / 4 No. 3 No. 15
C00004570 External link 512 Ermanin
/ Kaempferol 3,4'-di-O-methyl ether
/ 5,7-Dihydroxy-3,4'-dimethoxyflavone
/ 5,7-Dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL309061
C104804
2 / 1 / 1 No. 3 No. 15
C00004639 External link 512 Quercetin 3,3'-dimethyl ether
/ 5,7,4'-Trihydroxy-3,3'-dimethoxyflavone
/ 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-methoxy-4H-1-benzopyran-4-one
CHEMBL511363
C060385
No. 3 No. 15
C00004622 External link 512 Flindulatin
/ 3,7,8,4'-Tetramethylherbacetin
/ 5-Hydroxy-3,4',7,8-tetramethoxyflavone
/ 5-Hydroxy-3,7,8-trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL164899
No. 8 No. 15
C00004673 External link 512 5-Hydroxyauranetin
/ 5-Hydroxy-3,6,7,8,4'-pentamethoxyflavone
/ 5-Hydroxy-3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one
CHEMBL504047
No. 8 No. 15
C00013315 External link 512 4'-Hydroxy-5,6,7,8-tetramethoxyflavone
/ 2-(4-Hydroxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
CHEMBL479077
No. 8 No. 15

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00004570 1 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001060 0 / 0
P08183 Multidrug resistance protein 1 drug C00001060 1 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001060 4 / 4
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001060 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001060 2 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00001060 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00004570 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
#608902 Drug metabolism, poor, cyp2d6-related P10635
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#612244 Inflammatory bowel disease 13; ibd13 P08183
#604229 Peters anomaly Q16678
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)