PCIDB

Ovis aries

Species

KNApSAcK Entry

Organism name Ovis aries
Genus Ovis
Family Bovidae
Kingdom Animalia

NCBI taxonomy

Entry

Linked NCBI taxonomy name Ovis aries
Linked NCBI taxonomy ID 9940
Linked level species

Family

Family in NCBI taxonomy Bovidae
ID 9895

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Metazoa
ID 33208

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00000134 External link 512 (s)-(+)-Abscisic acid
/ 2,4-Pentadienoic acid
CHEMBL288040
CHEMBL379808
CHEMBL1318134
CHEMBL1469719
CHEMBL1741460
CHEMBL1965138
D000040
10 / 9 / 10 No. 1435 No. 38

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000134 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000134 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000134 0 / 1
P10145 Interleukin-8 Secreted protein C00000134 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000134 0 / 0
P03372 Estrogen receptor NR3A1 C00000134 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000134 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000134 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000134 0 / 0
P10275 Androgen receptor NR3C4 C00000134 3 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (10)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)