Nigrospora sp. PSU-F5
Metabolite list (9)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000134
|
(s)-(+)-Abscisic acid
/ 2,4-Pentadienoic acid |
CHEMBL288040
CHEMBL379808 CHEMBL1318134 CHEMBL1469719 CHEMBL1741460 CHEMBL1965138 |
D000040
|
10 / 9 / 10 | No. 1435 | No. 38 |
|
|
|
C00023642
|
Epoxydone
/ (+)-Epoxydon / (+)-Parasitenone |
CHEMBL443078
CHEMBL477749 |
No. 1589 |
|
||||
|
C00038084
|
(+)-Phaseic acid
|
No. 2610 | No. 38 |
|
||||
|
C00039848
|
Nigrosporapyrone
/ (-)-Nigrosporapyrone |
No. 3225 |
|
|||||
|
C00039974
|
Pestalopyrone
|
CHEMBL454237
|
No. 3588 |
|
||||
|
C00038256
|
3-Hydroxymethylphenol
|
No. 4008 |
|
|||||
|
C00039849
|
Nigrospoxydon A
/ (+)-Nigrospoxydon A |
CHEMBL526455
|
No. 5354 |
|
||||
|
C00039850
|
Nigrospoxydon B
/ (+)-Nigrospoxydon B |
CHEMBL498693
|
No. 6971 |
|
||||
|
C00039851
|
Nigrospoxydon C
/ (+)-Nigrospoxydon C |
CHEMBL497687
|
No. 8242 |
|
Human Protein / Gene in interactions
10 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000134 | 1 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000134 | 3 / 2 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000134 | 0 / 1 |
| P10145 | Interleukin-8 | Secreted protein | C00000134 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000134 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00000134 | 1 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000134 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000134 | 0 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000134 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00000134 | 3 / 4 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|