| Organism name | Griffonia simplicifolia | 
|---|---|
| Genus | Griffonia | 
| Family | Fabaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Griffonia simplicifolia | 
|---|---|
| Linked NCBI taxonomy ID | 3850 | 
| Linked level | species | 
| Family in NCBI taxonomy | Fabaceae | 
|---|---|
| ID | 3803 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00001371   | 5-Hydroxy-L-tryptophan | CHEMBL350221 CHEMBL162789 | 27 / 34 / 26 | No. 1910 | No. 4 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001371 | 0 / 0 | 
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001371 | 0 / 0 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001371 | 2 / 0 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00001371 | 11 / 10 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001371 | 3 / 2 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001371 | 3 / 1 | 
| P54132 | Bloom syndrome protein | Enzyme | C00001371 | 1 / 2 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001371 | 0 / 0 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001371 | 1 / 2 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001371 | 0 / 0 | 
| P04150 | Glucocorticoid receptor | NR3C1 | C00001371 | 0 / 1 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001371 | 3 / 3 | 
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001371 | 5 / 2 | 
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00001371 | 0 / 0 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001371 | 0 / 0 | 
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001371 | 0 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001371 | 0 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001371 | 0 / 0 | 
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00001371 | 1 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001371 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001371 | 4 / 3 | 
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001371 | 0 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001371 | 0 / 0 | 
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00001371 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001371 | 0 / 0 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001371 | 0 / 0 | 
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001371 | 0 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #608584 | Asthma-related traits, susceptibility to, 2 | Q6W5P4 | 
| #210900 | Bloom syndrome; blm | P54132 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #118300 | Charcot-marie-tooth disease and deafness | Q01453 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a | Q01453 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #139393 | Guillain-barre syndrome, familial; gbs | Q01453 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #145900 | Hypertrophic neuropathy of dejerine-sottas | Q01453 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp | Q01453 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #604906 | Schizophrenia 9; sczd9 | P49798 | 
| #181500 | Schizophrenia; sczd | P49798 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | P10828 | 
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | P10828 | 
| #145650 | Thyroid hormone resistance, selective pituitary; prth | P10828 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) Q01453 (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) | P04150
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00249 | Thyroid hormone resistance syndrome | P10828
                            (related) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P16473
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H00094 | DNA repair defects | P54132
                            (related) | 
| H00296 | Defects in RecQ helicases | P54132
                            (related) | 
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) | Q01453
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) |