Organism name | Coffea liberica |
---|---|
Genus | Coffea |
Family | Rubiaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Coffea liberica |
---|---|
Linked NCBI taxonomy ID | 49373 |
Linked level | species |
Family in NCBI taxonomy | Rubiaceae |
---|---|
ID | 24966 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | asterids |
---|---|
ID | 71274 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00001492
![]() |
Caffeine
|
CHEMBL113
|
D002110
|
115 / 59 / 49 | 109 / 161 | No. 3446 | No. 12 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P11217 | Glycogen phosphorylase, muscle form | Enzyme | C00001492 | 1 / 1 |
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001492 | 1 / 0 |
P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001492 | 0 / 0 |
Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00001492 | 1 / 0 |
O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00001492 | 0 / 0 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001492 | 0 / 0 |
P27338 | Amine oxidase [flavin-containing] B | Oxidoreductase | C00001492 | 0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001492 | 0 / 3 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001492 | 2 / 2 |
P08246 | Neutrophil elastase | S1A | C00001492 | 2 / 1 |
P33765 | Adenosine receptor A3 | Adenosine receptor | C00001492 | 0 / 0 |
P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | C00001492 | 0 / 0 |
Q16539 | Mitogen-activated protein kinase 14 | p38 | C00001492 | 0 / 0 |
P06746 | DNA polymerase beta | Enzyme | C00001492 | 0 / 0 |
P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00001492 | 0 / 0 |
Q9Y2T3 | Guanine deaminase | Enzyme | C00001492 | 0 / 0 |
P29466 | Caspase-1 | C14 | C00001492 | 0 / 0 |
P17252 | Protein kinase C alpha type | Alpha | C00001492 | 0 / 0 |
P27361 | Mitogen-activated protein kinase 3 | Erk | C00001492 | 0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | C00001492 | 2 / 2 |
Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00001492 | 1 / 4 |
O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00001492 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00001492 | 3 / 1 |
P29275 | Adenosine receptor A2b | Adenosine receptor | C00001492 | 0 / 0 |
P00918 | Carbonic anhydrase 2 | Lyase | C00001492 | 1 / 2 |
P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00001492 | 0 / 1 |
P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00001492 | 1 / 1 |
P25021 | Histamine H2 receptor | Histamine receptor | C00001492 | 0 / 0 |
P35367 | Histamine H1 receptor | Histamine receptor | C00001492 | 0 / 0 |
Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00001492 | 1 / 0 |
P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00001492 | 0 / 0 |
P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00001492 | 0 / 0 |
P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00001492 | 0 / 0 |
P02768 | Serum albumin | Secreted protein | C00001492 | 0 / 0 |
P08183 | Multidrug resistance protein 1 | drug | C00001492 | 1 / 0 |
P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00001492 | 0 / 0 |
P06241 | Tyrosine-protein kinase Fyn | Src | C00001492 | 0 / 0 |
Q08828 | Adenylate cyclase type 1 | Enzyme | C00001492 | 0 / 0 |
Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00001492 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001492 | 0 / 1 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00001492 | 1 / 8 |
P14416 | D(2) dopamine receptor | Dopamine receptor | C00001492 | 2 / 0 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001492 | 0 / 0 |
P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00001492 | 0 / 0 |
P41145 | Kappa-type opioid receptor | Opioid receptor | C00001492 | 0 / 0 |
Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00001492 | 0 / 0 |
P29274 | Adenosine receptor A2a | Adenosine receptor | C00001492 | 0 / 0 |
P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00001492 | 0 / 0 |
P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00001492 | 1 / 1 |
P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00001492 | 0 / 0 |
P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00001492 | 1 / 0 |
P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00001492 | 0 / 0 |
O75496 | Geminin | Unclassified protein | C00001492 | 0 / 0 |
P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00001492 | 0 / 0 |
P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00001492 | 0 / 0 |
P21917 | D(4) dopamine receptor | Dopamine receptor | C00001492 | 0 / 0 |
P30988 | Calcitonin receptor | Calcitonin receptor | C00001492 | 0 / 0 |
P35462 | D(3) dopamine receptor | Dopamine receptor | C00001492 | 1 / 0 |
P41143 | Delta-type opioid receptor | Opioid receptor | C00001492 | 0 / 0 |
Q92731 | Estrogen receptor beta | NR3A2 | C00001492 | 0 / 1 |
P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00001492 | 0 / 0 |
P25101 | Endothelin-1 receptor | Endothelin receptor | C00001492 | 0 / 0 |
P30411 | B2 bradykinin receptor | Bradykinin receptor | C00001492 | 0 / 0 |
P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00001492 | 1 / 0 |
P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00001492 | 0 / 0 |
P08311 | Cathepsin G | S1A | C00001492 | 0 / 0 |
Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00001492 | 1 / 0 |
P03956 | Interstitial collagenase | M10A | C00001492 | 0 / 1 |
Q13535 | Serine/threonine-protein kinase ATR | Atypical serine/threonine protein kinase PIKK subfamily | C00001492 | 2 / 2 |
P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00001492 | 0 / 0 |
P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001492 | 0 / 0 |
Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00001492 | 1 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00001492 | 0 / 1 |
P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00001492 | 2 / 0 |
P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00001492 | 0 / 0 |
P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00001492 | 0 / 0 |
P31645 | Sodium-dependent serotonin transporter | Serotonin | C00001492 | 2 / 0 |
P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00001492 | 5 / 9 |
P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00001492 | 1 / 0 |
P21452 | Substance-K receptor | Neurokinin receptor | C00001492 | 0 / 0 |
P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00001492 | 0 / 0 |
P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00001492 | 3 / 0 |
P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00001492 | 0 / 0 |
P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00001492 | 1 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00001492 | 0 / 0 |
P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00001492 | 2 / 1 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001492 | 0 / 0 |
O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00001492 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00001492 | 1 / 1 |
P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00001492 | 1 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00001492 | 1 / 0 |
P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001492 | 0 / 0 |
P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00001492 | 0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00001492 | 0 / 0 |
P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00001492 | 0 / 0 |
P25103 | Substance-P receptor | Neurokinin receptor | C00001492 | 0 / 0 |
P25105 | Platelet-activating factor receptor | PAF receptor | C00001492 | 0 / 0 |
P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00001492 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001492 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001492 | 0 / 1 |
P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00001492 | 0 / 0 |
P10275 | Androgen receptor | NR3C4 | C00001492 | 3 / 4 |
P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00001492 | 1 / 1 |
P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00001492 | 0 / 0 |
P30542 | Adenosine receptor A1 | Adenosine receptor | C00001492 | 0 / 0 |
P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00001492 | 0 / 0 |
P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00001492 | 1 / 1 |
P06239 | Tyrosine-protein kinase Lck | Src | C00001492 | 0 / 1 |
P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00001492 | 0 / 0 |
P04156 | Major prion protein | Surface antigen | C00001492 | 6 / 2 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00001492 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001492 | 0 / 0 |
Q9NY46 | Sodium channel protein type 3 subunit alpha | SCN alpha, NaV1.x | C00001492 | 0 / 0 |
Q99250 | Sodium channel protein type 2 subunit alpha | SCN alpha, NaV1.x | C00001492 | 2 / 2 |
P35498 | Sodium channel protein type 1 subunit alpha | SCN alpha, NaV1.x | C00001492 | 3 / 2 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
39 | ACAT2 | acetyl-CoA acetyltransferase 2 (EC:2.3.1.9) |
C00001492
|
22985 | ACIN1, ACINUS, ACN, fSAP152 | apoptotic chromatin condensation inducer 1 |
C00001492
|
2181 | ACSL3, ACS3, FACL3, PRO2194 | acyl-CoA synthetase long-chain family member 3 (EC:6.2.1.3) |
C00001492
|
135 | ADORA2A, A2aR, ADORA2, RDC8 | adenosine A2a receptor |
C00001492
|
136 | ADORA2B, ADORA2 | adenosine A2b receptor |
C00001492
|
207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00001492
|
5832 | ALDH18A1, ARCL3A, GSAS, P5CS, PYCS | aldehyde dehydrogenase 18 family, member A1 (EC:1.2.1.41 2.7.2.11) |
C00001492
|
283 | ANG, ALS9, HEL168, RNASE4, RNASE5 | angiogenin, ribonuclease, RNase A family, 5 (EC:3.1.27.-) |
C00001492
|
335 | APOA1 | apolipoprotein A-I |
C00001492
|
336 | APOA2, Apo-AII, ApoA-II, apoAII | apolipoprotein A-II |
C00001492
|
338 | APOB, FLDB, LDLCQ4 | apolipoprotein B |
C00001492
|
341 | APOC1 | apolipoprotein C-I |
C00001492
|
344 | APOC2, APO-CII, APOC-II | apolipoprotein C-II |
C00001492
|
345 | APOC3, APOCIII, HALP2 | apolipoprotein C-III |
C00001492
|
23204 | ARL6IP1, AIP1, ARL6IP, ARMER | ADP-ribosylation factor-like 6 interacting protein 1 |
C00001492
|
440 | ASNS, TS11 | asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4) |
C00001492
|
472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00001492
|
9551 | ATP5J2, ATP5JL | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 (EC:3.6.1.14) |
C00001492
|
545 | ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1 | ataxia telangiectasia and Rad3 related (EC:2.7.11.1) |
C00001492
|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00001492
|
27113 | BBC3, JFY-1, JFY1, PUMA | BCL2 binding component 3 |
C00001492
|
637 | BID, FP497 | BH3 interacting domain death agonist |
C00001492
|
699 | BUB1, BUB1A, BUB1L, hBUB1 | BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1) |
C00001492
|
813 | CALU | calumenin |
C00001492
|
823 | CAPN1, CANP, CANP1, CANPL1, muCANP, muCL | calpain 1, (mu/I) large subunit (EC:3.4.22.52) |
C00001492
|
835 | CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57 | caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55) |
C00001492
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001492
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001492
|
891 | CCNB1, CCNB | cyclin B1 |
C00001492
|
995 | CDC25C, CDC25, PPP1R60 | cell division cycle 25C (EC:3.1.3.48) |
C00001492
|
983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00001492
|
1017 | CDK2, p33(CDK2) | cyclin-dependent kinase 2 (EC:2.7.11.22) |
C00001492
|
1019 | CDK4, CMM3, PSK-J3 | cyclin-dependent kinase 4 (EC:2.7.11.22) |
C00001492
|
1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001492
|
1111 | CHEK1, CHK1 | checkpoint kinase 1 (EC:2.7.11.1) |
C00001492
|
11200 | CHEK2, CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1 | checkpoint kinase 2 (EC:2.7.11.1) |
C00001492
|
1508 | CTSB, APPS, CPSB | cathepsin B (EC:3.4.22.1) |
C00001492
|
1537 | CYC1, MC3DN6, UQCR4 | cytochrome c-1 |
C00001492
|
54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00001492
|
1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00001492
|
1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00001492
|
1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00001492
|
1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00001492
|
1580 | CYP4B1, CYPIVB1, P-450HP | cytochrome P450, family 4, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001492
|
1603 | DAD1, OST2 | defender against cell death 1 (EC:2.4.99.18) |
C00001492
|
1638 | DCT, TRP-2, TYRP2 | dopachrome tautomerase (EC:5.3.3.12) |
C00001492
|
1813 | DRD2, D2DR, D2R | dopamine receptor D2 |
C00001492
|
10209 | EIF1, A121, EIF-1, EIF1A, ISO1, SUI1 | eukaryotic translation initiation factor 1 |
C00001492
|
1978 | EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I | eukaryotic translation initiation factor 4E binding protein 1 |
C00001492
|
2688 | GH1, GH, GH-N, GHN, IGHD1B, hGH-N | growth hormone 1 |
C00001492
|
2745 | GLRX, GRX, GRX1 | glutaredoxin (thioltransferase) (EC:1.8.4.1) |
C00001492
|
55830 | GLT8D1, MSTP139 | glycosyltransferase 8 domain containing 1 |
C00001492
|
2746 | GLUD1, GDH, GDH1, GLUD | glutamate dehydrogenase 1 (EC:1.4.1.3) |
C00001492
|
2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00001492
|
9446 | GSTO1, GSTO_1-1, GSTTLp28, P28, SPG-R | glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2) |
C00001492
|
3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00001492
|
3291 | HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3 | hydroxysteroid (11-beta) dehydrogenase 2 (EC:1.1.1.146) |
C00001492
|
3484 | IGFBP1, AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1 | insulin-like growth factor binding protein 1 |
C00001492
|
3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00001492
|
3708 | ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29 | inositol 1,4,5-trisphosphate receptor, type 1 |
C00001492
|
3939 | LDHA, GSD11, LDH1, LDHM | lactate dehydrogenase A (EC:1.1.1.27) |
C00001492
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00001492
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00001492
|
4257 | MGST1, GST12, MGST, MGST-I | microsomal glutathione S-transferase 1 (EC:2.5.1.18) |
C00001492
|
4277 | MICB, PERB11.2 | MHC class I polypeptide-related sequence B |
C00001492
|
4495 | MT1G, MT1, MT1K | metallothionein 1G |
C00001492
|
2475 | MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 | mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1) |
C00001492
|
10 | NAT2, AAC2, NAT-2, PNAT | N-acetyltransferase 2 (arylamine N-acetyltransferase) (EC:2.3.1.5) |
C00001492
|
4942 | OAT, GACR, HOGA, OATASE, OKT | ornithine aminotransferase (EC:2.6.1.13) |
C00001492
|
5062 | PAK2, PAK65, PAKgamma | p21 protein (Cdc42/Rac)-activated kinase 2 (EC:2.7.11.1) |
C00001492
|
142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001492
|
5354 | PLP1, GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2 | proteolipid protein 1 |
C00001492
|
5521 | PPP2R2B, B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12 | protein phosphatase 2, regulatory subunit B, beta (EC:3.1.3.16) |
C00001492
|
27166 | PRELID1, PRELI, PX19, SBBI12 | PRELI domain containing 1 |
C00001492
|
5591 | PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 | protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1) |
C00001492
|
5621 | PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30 | prion protein |
C00001492
|
10197 | PSME3, Ki, PA28-gamma, PA28G, PA28gamma, REG-GAMMA | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) |
C00001492
|
5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00001492
|
5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00001492
|
5972 | REN, HNFJ2 | renin (EC:3.4.23.15) |
C00001492
|
6194 | RPS6, S6 | ribosomal protein S6 |
C00001492
|
6197 | RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1) |
C00001492
|
6198 | RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha | ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1) |
C00001492
|
23212 | RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
C00001492
|
6261 | RYR1, CCO, MHS, MHS1, RYDR, RYR, RYR-1, SKRR | ryanodine receptor 1 (skeletal) |
C00001492
|
23256 | SCFD1, C14orf163, RA410, SLY1, SLY1P, STXBP1L2 | sec1 family domain containing 1 |
C00001492
|
6396 | SEC13, D3S1231E, SEC13L1, SEC13R, npp-20 | SEC13 homolog (S. cerevisiae) |
C00001492
|
10484 | SEC23A, CLSD | Sec23 homolog A (S. cerevisiae) |
C00001492
|
5265 | SERPINA1, A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
C00001492
|
866 | SERPINA6, CBG | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 |
C00001492
|
6566 | SLC16A1, HHF7, MCT, MCT1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
C00001492
|
54498 | SMOX, C20orf16, PAO, PAO-1, PAOH1, SMO | spermine oxidase (EC:1.5.3.16) |
C00001492
|
6713 | SQLE | squalene epoxidase (EC:1.14.13.132) |
C00001492
|
8878 | SQSTM1, A170, OSIL, PDB3, ZIP3, p60, p62, p62B | sequestosome 1 |
C00001492
|
6426 | SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a | serine/arginine-rich splicing factor 1 |
C00001492
|
6770 | STAR, STARD1 | steroidogenic acute regulatory protein |
C00001492
|
55342 | STRBP, ILF3L, SPNR, p74 | spermatid perinuclear RNA binding protein |
C00001492
|
7027 | TFDP1, DP1, DRTF1, Dp-1 | transcription factor Dp-1 |
C00001492
|
10548 | TM9SF1, HMP70, MP70 | transmembrane 9 superfamily member 1 |
C00001492
|
9911 | TMCC2, HUCEP11 | transmembrane and coiled-coil domain family 2 |
C00001492
|
27346 | TMEM97, MAC30 | transmembrane protein 97 |
C00001492
|
7292 | TNFSF4, CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1 | tumor necrosis factor (ligand) superfamily, member 4 |
C00001492
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001492
|
7296 | TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR | thioredoxin reductase 1 (EC:1.8.1.9) |
C00001492
|
54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00001492
|
7385 | UQCRC2, MC3DN5, QCR2, UQCR2 | ubiquinol-cytochrome c reductase core protein II (EC:1.10.2.2) |
C00001492
|
7498 | XDH, XO, XOR | xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) |
C00001492
|
10971 | YWHAQ, 14-3-3, 1C5, HS1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide |
C00001492
|
7587 | ZNF37A, KOX21, ZNF37 | zinc finger protein 37A |
C00001492
|
OMIM | preferred title | UniProt |
---|---|---|
#100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
#103780 | Alcohol dependence |
P08172
P14416 P31645 |
#614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
#300068 | Androgen insensitivity syndrome; ais |
P10275
|
#312300 | Androgen insensitivity, partial; pais |
P10275
|
#208900 | Ataxia-telangiectasia; at |
Q13315
|
#602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
#300615 | Brunner syndrome |
P21397
|
#123400 | Creutzfeldt-jakob disease; cjd |
P04156
|
#614564 | Cutaneous telangiectasia and cancer syndrome, familial; fctcs |
Q13535
|
#162800 | Cyclic neutropenia |
P08246
|
#612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
#607208 | Dravet syndrome |
P35498
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#613721 | Epileptic encephalopathy, early infantile, 11; eiee11 |
Q99250
|
#615363 | Estrogen resistance; estrr |
P03372
|
#600072 | Fatal familial insomnia; ffi |
P04156
|
#613659 | Gastric cancer |
P04626
|
#137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
#604403 | Generalized epilepsy with febrile seizures plus, type 2; gefsp2 |
P35498
|
#137440 | Gerstmann-straussler disease; gsd |
P04156
|
#231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
#137800 | Glioma susceptibility 1; glm1 |
P04626
|
#232600 | Glycogen storage disease v |
P11217
|
#609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
#603218 | Huntington disease-like 1; hdl1 |
P04156
|
#237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
#612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
#603932 | Intervertebral disc disease; idd |
P14780
|
#245300 | Kuru, susceptibility to |
P04156
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P00533
P04626 |
#608516 | Major depressive disorder; mdd |
P08172
|
%300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#609634 | Migraine, familial hemiplegic, 3; fhm3 |
P35498
|
#126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
#159900 | Myoclonic dystonia |
P14416
|
#202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
#601665 | Obesity |
P32245
|
#164230 | Obsessive-compulsive disorder; ocd |
P31645
|
#604715 | Orthostatic intolerance |
P23975
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#167000 | Ovarian cancer |
P04626
|
#613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
#607276 | Resting heart rate, variation in |
P08588
|
#210600 | Seckel syndrome 1; sckl1 |
Q13535
|
#607745 | Seizures, benign familial infantile, 3; bfis3 |
Q99250
|
#608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
#606688 | Spongiform encephalopathy with neuropsychiatric features |
P04156
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
#610379 | West nile virus, susceptibility to |
P51681
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
H00042 | Glioma |
P00533
(related)
P00533 (marker) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00061 | Prion diseases |
P04156
(related)
|
H01243 | Huntington's disease-like syndrome |
P04156
(related)
|
H00019 | Pancreatic cancer |
P04626
(related)
|
H00027 | Ovarian cancer |
P04626
(related)
|
H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
H00079 | Asthma |
P07550
(related)
|
H00100 | Neutropenic disorders |
P08246
(related)
|
H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00024 | Prostate cancer |
P10275
(related)
|
H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00069 | Glycogen storage diseases (GSD) |
P11217
(related)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
H00479 | Metaphyseal dysplasias |
P14780
(related)
|
H00548 | Brunner syndrome |
P21397
(related)
|
H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00775 | Familial or sporadic hemiplegic migraine |
P35498
(related)
|
H00783 | Febrile seizures |
P35498
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
H00094 | DNA repair defects |
Q13315
(related)
|
H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
H00037 | Alveolar rhabdomyosarcoma |
Q13535
(related)
|
H00992 | Seckel syndrome |
Q13535
(related)
|
H00606 | Early infantile epileptic encephalopathy |
Q99250
(related)
|
H00806 | Benign familial neonatal and infantile epilepsies |
Q99250
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D000014 | Abnormalities, Drug-Induced |
C00001492
|
D000015 | Abnormalities, Multiple |
C00001492
|
D000230 | Adenocarcinoma |
C00001492
|
D000236 | Adenoma |
C00001492
|
D017542 | Aneurysm, Ruptured |
C00001492
|
D001008 | Anxiety Disorders |
C00001492
|
D001018 | Aortic Diseases |
C00001492
|
D001049 | Apnea |
C00001492
|
D001167 | Arteritis |
C00001492
|
D001281 | Atrial Fibrillation |
C00001492
|
D001282 | Atrial Flutter |
C00001492
|
D054537 | Atrioventricular Block |
C00001492
|
D001289 | Attention Deficit Disorder with Hyperactivity |
C00001492
|
D001480 | Basal Ganglia Diseases |
C00001492
|
D001714 | Bipolar Disorder |
C00001492
|
D001766 | Blindness |
C00001492
|
D018488 | Bone Demineralization, Pathologic |
C00001492
|
D001929 | Brain Edema |
C00001492
|
D001930 | Brain Injuries |
C00001492
|
D001943 | Breast Neoplasms |
C00001492
|
D002294 | Carcinoma, Squamous Cell |
C00001492
|
D002295 | Carcinoma, Transitional Cell |
C00001492
|
D009202 | Cardiomyopathies |
C00001492
|
D002318 | Cardiovascular Diseases |
C00001492
|
D002375 | Catalepsy |
C00001492
|
D002389 | Catatonia |
C00001492
|
D002543 | Cerebral Hemorrhage |
C00001492
|
D023341 | Chills |
C00001492
|
D019970 | Cocaine-Related Disorders |
C00001492
|
D003072 | Cognition Disorders |
C00001492
|
D003110 | Colonic Neoplasms |
C00001492
|
D003327 | Coronary Disease |
C00001492
|
D003329 | Coronary Vasospasm |
C00001492
|
D003645 | Death, Sudden |
C00001492
|
D003866 | Depressive Disorder |
C00001492
|
D003967 | Diarrhea |
C00001492
|
D004065 | Digestive System Abnormalities |
C00001492
|
D004195 | Disease Models, Animal |
C00001492
|
D004244 | Dizziness |
C00001492
|
D003875 | Drug Eruptions |
C00001492
|
D064420 | Drug-Related Side Effects and Adverse Reactions |
C00001492
|
D004409 | Dyskinesia, Drug-Induced |
C00001492
|
D004487 | Edema |
C00001492
|
D004715 | Endometriosis |
C00001492
|
D004830 | Epilepsy, Tonic-Clonic |
C00001492
|
D005234 | Fatty Liver |
C00001492
|
D005317 | Fetal Growth Retardation |
C00001492
|
D005327 | Fetal Resorption |
C00001492
|
D005334 | Fever |
C00001492
|
D005348 | Fibrocystic Breast Disease |
C00001492
|
D005355 | Fibrosis |
C00001492
|
D005767 | Gastrointestinal Diseases |
C00001492
|
D005831 | Genital Diseases, Female |
C00001492
|
D005832 | Genital Diseases, Male |
C00001492
|
D005923 | Glomerulosclerosis, Focal Segmental |
C00001492
|
D006029 | Glycosuria |
C00001492
|
D006130 | Growth Disorders |
C00001492
|
D006212 | Hallucinations |
C00001492
|
D006261 | Headache |
C00001492
|
D006323 | Heart Arrest |
C00001492
|
D006330 | Heart Defects, Congenital |
C00001492
|
D006331 | Heart Diseases |
C00001492
|
D006345 | Heart Septal Defects, Ventricular |
C00001492
|
D006417 | Hematuria |
C00001492
|
D006470 | Hemorrhage |
C00001492
|
D006505 | Hepatitis |
C00001492
|
D006620 | Hip Fractures |
C00001492
|
D006849 | Hydrocephalus |
C00001492
|
D006930 | Hyperalgesia |
C00001492
|
D006940 | Hyperemia |
C00001492
|
D006941 | Hyperesthesia |
C00001492
|
D006948 | Hyperkinesis |
C00001492
|
D006965 | Hyperplasia |
C00001492
|
D006973 | Hypertension |
C00001492
|
D006974 | Hypertension, Malignant |
C00001492
|
D006977 | Hypertension, Renal |
C00001492
|
D020343 | Hypertensive Encephalopathy |
C00001492
|
D007008 | Hypokalemia |
C00001492
|
D007022 | Hypotension |
C00001492
|
D007035 | Hypothermia |
C00001492
|
D007235 | Infant, Premature, Diseases |
C00001492
|
D007249 | Inflammation |
C00001492
|
D007333 | Insulin Resistance |
C00001492
|
D007674 | Kidney Diseases |
C00001492
|
D007680 | Kidney Neoplasms |
C00001492
|
D007681 | Kidney Papillary Necrosis |
C00001492
|
D007683 | Kidney Tubular Necrosis, Acute |
C00001492
|
D007859 | Learning Disorders |
C00001492
|
D007905 | Lens Diseases |
C00001492
|
D017114 | Liver Failure, Acute |
C00001492
|
D008113 | Liver Neoplasms |
C00001492
|
D008133 | Long QT Syndrome |
C00001492
|
D008175 | Lung Neoplasms |
C00001492
|
D008206 | Lymphatic Diseases |
C00001492
|
D015674 | Mammary Neoplasms, Animal |
C00001492
|
D008325 | Mammary Neoplasms, Experimental |
C00001492
|
D008569 | Memory Disorders |
C00001492
|
D008881 | Migraine Disorders |
C00001492
|
D019964 | Mood Disorders |
C00001492
|
D019957 | Motor Skills Disorders |
C00001492
|
D009069 | Movement Disorders |
C00001492
|
D020267 | MPTP Poisoning |
C00001492
|
D009120 | Muscle Cramp |
C00001492
|
D018908 | Muscle Weakness |
C00001492
|
D009135 | Muscular Diseases |
C00001492
|
D009139 | Musculoskeletal Abnormalities |
C00001492
|
D009203 | Myocardial Infarction |
C00001492
|
D017202 | Myocardial Ischemia |
C00001492
|
D009325 | Nausea |
C00001492
|
D009336 | Necrosis |
C00001492
|
D009357 | Neonatal Abstinence Syndrome |
C00001492
|
D009374 | Neoplasms, Experimental |
C00001492
|
D009395 | Nephritis, Interstitial |
C00001492
|
D009436 | Neural Tube Defects |
C00001492
|
D009765 | Obesity |
C00001492
|
D009798 | Ocular Hypertension |
C00001492
|
D010024 | Osteoporosis |
C00001492
|
D010146 | Pain |
C00001492
|
D016584 | Panic Disorder |
C00001492
|
D010300 | Parkinson Disease |
C00001492
|
C537181 | Paroxysmal nonkinesigenic dyskinesia |
C00001492
|
D010911 | Pituitary Neoplasms |
C00001492
|
D010922 | Placenta Diseases |
C00001492
|
D010488 | Polyarteritis Nodosa |
C00001492
|
D011141 | Polyuria |
C00001492
|
D051299 | Post-Dural Puncture Headache |
C00001492
|
D011230 | Precancerous Conditions |
C00001492
|
D011297 | Prenatal Exposure Delayed Effects |
C00001492
|
D011507 | Proteinuria |
C00001492
|
D011596 | Psychomotor Disorders |
C00001492
|
D011605 | Psychoses, Substance-Induced |
C00001492
|
D012148 | Restless Legs Syndrome |
C00001492
|
D012509 | Sarcoma |
C00001492
|
D012512 | Sarcoma, Ewing |
C00001492
|
D012559 | Schizophrenia |
C00001492
|
D012640 | Seizures |
C00001492
|
D012652 | Self Mutilation |
C00001492
|
D012878 | Skin Neoplasms |
C00001492
|
D012892 | Sleep Deprivation |
C00001492
|
D012893 | Sleep Disorders |
C00001492
|
D007319 | Sleep Initiation and Maintenance Disorders |
C00001492
|
D013272 | Stomach Diseases |
C00001492
|
D013274 | Stomach Neoplasms |
C00001492
|
D020521 | Stroke |
C00001492
|
D013345 | Subarachnoid Hemorrhage |
C00001492
|
D019966 | Substance-Related Disorders |
C00001492
|
D013375 | Substance Withdrawal Syndrome |
C00001492
|
D013575 | Syncope |
C00001492
|
D013610 | Tachycardia |
C00001492
|
D013614 | Tachycardia, Paroxysmal |
C00001492
|
D013617 | Tachycardia, Supraventricular |
C00001492
|
D017180 | Tachycardia, Ventricular |
C00001492
|
C572845 | Thyroid cancer, follicular |
C00001492
|
D013981 | Tic Disorders |
C00001492
|
D014202 | Tremor |
C00001492
|
D014516 | Ureteral Neoplasms |
C00001492
|
D014555 | Urination Disorders |
C00001492
|
D014581 | Urticaria |
C00001492
|
D014693 | Ventricular Fibrillation |
C00001492
|
D018879 | Ventricular Premature Complexes |
C00001492
|
D015431 | Weight Loss |
C00001492
|