Species

KNApSAcK Entry

Organism name Santolina rosmarinifolia subsp. canescens
Genus Santolina
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Santolina
Linked NCBI taxonomy ID 41642
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003650 External link 512 Cycloartenol
CHEMBL119938
CHEMBL225815
CHEMBL226036
CHEMBL393145
CHEMBL2007217
C100089
0 / 1 No. 129 No. 11
C00012773 External link 512 Pigmol
/ Pygmol
/ [1R-(1alpha,4abeta,7beta,8alpha,8aalpha)]-Decahydro-7-(1-hydroxy-1-methylethyl)-1,4a-dimethyl-1,8-naphthalenediol
No. 351
C00012765 External link 512 Proximadiol
/ Cryptomeridiol
/ Selina-4,7-diol
/ Selinane-4alpha,11-diol
CHEMBL465860
CHEMBL1288770
No. 351
C00011617 External link 512 AR-Curcumene
/ (R)-(-)-alpha-Curcumene
CHEMBL469717
No. 456 No. 38
C00011607 External link 512 (-)-alpha-Bisabolol
CHEMBL519167
CHEMBL491186
CHEMBL477832
CHEMBL1096927
CHEMBL1171719
CHEMBL1561544
CHEMBL2104360
8 / 4 / 13 No. 541 No. 38
C00000149 External link 512 Spathulenol
CHEMBL518542
CHEMBL1774433
C013258
No. 1603
C00011708 External link 512 Shiromool
No. 3093

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00011607 0 / 3
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00011607 1 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00011607 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00011607 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00011607 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00011607 0 / 1
O00255 Menin Unclassified protein C00011607 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00011607 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (13)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D012878 Skin Neoplasms C00003650