Species

KNApSAcK Entry

Organism name Alstonia constricta
Genus Alstonia
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Alstonia
Linked NCBI taxonomy ID 52821
Linked level genus

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (5)

Species Activity
Alstonia constricta F. Muell. Antipyretic
Alstonia constricta F. Muell. Antispasmodic
Alstonia constricta F. Muell. Hypotensive
Alstonia constricta F. Muell. Stimulant
Alstonia constricta F. Muell. Uterotonic

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00024336 External link 512 (-)-Vincamedine
CHEMBL600638
2 / 2 / 2 No. 507
C00024281 External link 512 Quebrachidine
/ (+)-Quebrachidine
C010318
No. 507
C00024296 External link 512 (-)-Vincamedine
/ O-Acetylvincamajine
/ Vincamajine acetate
CHEMBL600638
2 / 2 / 2 No. 507
C00024335 External link 512 (-)-Vincamajine
/ N-Methylquebrachidine
CHEMBL607365
2 / 2 / 2 No. 507
C00024331 External link 512 17-(3',4',5'-Trimethoxycinnamoyl)vincamajine
/ (-)-17-O-(3',4',5'-Trimethoxycinnamoyl)vincamajine
No. 1568
C00001683 External link 512 Alstonine
CHEMBL14755
CHEMBL1187439
CHEMBL1994588
1 / 1 / 0 No. 4006 No. 4

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P31639 Sodium/glucose cotransporter 2 Glucose C00024296 C00024335 C00024336 1 / 1
P13866 Sodium/glucose cotransporter 1 Glucose C00024296 C00024335 C00024336 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001683 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#608902 Drug metabolism, poor, cyp2d6-related P10635
#606824 Glucose/galactose malabsorption; ggm P13866
#233100 Renal glucosuria; glys1 P31639

KEGG DISEASE (2)

KEGG name UniProt
H01261 Congenital glucose-galactose malabsorption (GGM) P13866 (related)
H01126 Familial renal glucosuria (FRG) P31639 (related)