Species

KNApSAcK Entry

Organism name Isotoma longiflora
Genus Isotoma
Family Campanulaceae / Lobeliaceae
Kingdom Plantae

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002051 External link 512 Lobelanidine
CHEMBL122676
CHEMBL1473116
CHEMBL1906848
6 / 2 / 3 No. 3195 No. 1

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002051 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002051 0 / 1
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00002051 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002051 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002051 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002051 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)