Species

KNApSAcK Entry

Organism name Allium spp.
Genus Allium
Family Alliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Allium
Linked NCBI taxonomy ID 4678
Linked level genus

Family

Family in NCBI taxonomy Amaryllidaceae
ID 4668

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000212 External link 512 Lunularic acid
CHEMBL240495
C067452
No. 3522 No. 26
C00001245 External link 512 Dimethyl disulfide
CHEMBL1347061
C021181
4 / 4 / 6 No. 4703
C00001257 External link 512 Methyl allyl disulfide
C054528
No. 6783
C00001247 External link 512 Dipropyl disulfide
C041288
3 / 0 No. 8883

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00001245 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001245 3 / 2
Q13951 Core-binding factor subunit beta Unclassified protein C00001245 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001245 1 / 4

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001247
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00001247
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00001247

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196

KEGG DISEASE (6)

KEGG name UniProt
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)