Species

KNApSAcK Entry

Organism name Crossostylis sebertii
Genus Crossostylis
Family Rhizophoraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Crossostylis
Linked NCBI taxonomy ID 61135
Linked level genus

Family

Family in NCBI taxonomy Rhizophoraceae
ID 40029

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025552 External link 512 Benzoyltropine
/ O-Benzoyltropine
/ 3alpha-Benzoyloxytropane
CHEMBL419588
CHEMBL509945
CHEMBL1947051
CHEMBL1947052
CHEMBL2113329
5 / 2 / 1 No. 666 No. 1
C00002306 External link 512 Tropine
CHEMBL113555
CHEMBL1356617
CHEMBL2165231
C005864
6 / 13 / 13 No. 2640 No. 1
C00002281 External link 512 Brugine
No. 7995 No. 1

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002306 1 / 0
P02545 Prelamin-A/C Unclassified protein C00002306 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002306 0 / 1
P17787 Neuronal acetylcholine receptor subunit beta-2 CHRN beta C00025552 1 / 1
P43681 Neuronal acetylcholine receptor subunit alpha-4 CHRN alpha C00025552 1 / 1
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha C00025552 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002306 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002306 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002306 0 / 1
P46098 5-hydroxytryptamine receptor 3A NS C00025552 0 / 0
O95264 5-hydroxytryptamine receptor 3B NS C00025552 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600513 Epilepsy, nocturnal frontal lobe, 1; enfl1 P43681
#605375 Epilepsy, nocturnal frontal lobe, 3; enfl3 P17787
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (14)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00807 Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) P17787 (related)
P43681 (related)
H01171 Poor drug metabolism (PM) P33261 (related)