| Organism name | Taxus cuspidata Sieb et Zucc |
|---|---|
| Genus | Taxus |
| Family | Taxaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Taxus |
|---|---|
| Linked NCBI taxonomy ID | 25628 |
| Linked level | genus |
| Family in NCBI taxonomy | Taxaceae |
|---|---|
| ID | 25623 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00040457
|
Taxuspine J
|
CHEMBL403321
|
No. 137 |
|
||||
|
C00038289
|
5-Cinnamoyltaxicin I triacetate
|
CHEMBL128197
|
No. 137 |
|
||||
|
C00036220
|
Taxinine B
|
CHEMBL308259
|
No. 137 |
|
||||
|
C00002323
|
Taxol B
/ Cephalomannine |
CHEMBL305522
CHEMBL137681 CHEMBL400128 CHEMBL1314572 CHEMBL1397662 CHEMBL1473676 |
C056348
|
28 / 15 / 11 | No. 238 | No. 49 |
|
|
|
C00038159
|
Taxayuntin
/ 13-Decinnamoyl-taxchinin B |
CHEMBL340846
|
No. 307 |
|
||||
|
C00040455
|
Taxinine A 11,12-epoxide
/ (+)-Taxinine A 11,12-epoxide |
No. 481 |
|
|||||
|
C00037888
|
Taxinine M
|
CHEMBL309359
CHEMBL448698 CHEMBL1889966 |
C071771
|
7 / 1 / 1 | No. 1263 |
|
||
|
C00033406
|
Taxinine A
/ (-)-Taxinine A |
CHEMBL113940
|
No. 1557 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00002323 C00037888 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00002323 C00037888 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002323 C00037888 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00002323 C00037888 | 0 / 0 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002323 | 1 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00037888 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00002323 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00002323 | 2 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00037888 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00002323 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00002323 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00037888 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002323 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002323 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00002323 | 2 / 5 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00002323 | 0 / 0 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00002323 | 0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00002323 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00002323 | 1 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00002323 | 2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00002323 | 0 / 0 |
| P07437 | Tubulin beta chain | Structural | C00002323 | 0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00002323 | 1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00002323 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00002323 | 2 / 1 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00002323 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00002323 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00002323 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00002323 | 0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00002323 | 0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00002323 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|