Species

KNApSAcK Entry

Organism name Hippomane mancinella
Genus Hippomane
Family Euphorbiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hippomane mancinella
Linked NCBI taxonomy ID 316844
Linked level species

Family

Family in NCBI taxonomy Euphorbiaceae
ID 3977

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Natural Activity

List (27)

Species Activity
Hippomane mancinella L. Allergenic
Hippomane mancinella L. Allergenic
Hippomane mancinella L. Anticancer
Hippomane mancinella L. Carinogenic
Hippomane mancinella L. Cathartic
Hippomane mancinella L. Curare
Hippomane mancinella L. Curare
Hippomane mancinella L. Dermatitigenic
Hippomane mancinella L. Diaphoretic
Hippomane mancinella L. Diaphoretic
Hippomane mancinella L. Diarrheic
Hippomane mancinella L. Diuretic
Hippomane mancinella L. Diuretic
Hippomane mancinella L. Emetic
Hippomane mancinella L. Emetic
Hippomane mancinella L. Irritant
Hippomane mancinella L. Laxative
Hippomane mancinella L. Piscicide
Hippomane mancinella L. Piscicide
Hippomane mancinella L. Poison
Hippomane mancinella L. Poison
Hippomane mancinella L. toxic
Hippomane mancinella L. Tumorigenic
Hippomane mancinella L. Vermifuge
Hippomane mancinella L. Vermifuge
Hippomane mancinella L. Vesicant
Hippomane mancinella L. Vesicant

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002710 External link 512 Xanthoxylin
CHEMBL450288
C064382
6 / 4 / 2 No. 1180
C00003451 External link 512 Mancinellin
CHEMBL502052
No. 2074 No. 41

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00002710 4 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00002710 0 / 0
O75496 Geminin Unclassified protein C00002710 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002710 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002710 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002710 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (2)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)