PCIDB

Securigera cretica

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	rosids
ID	71275

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00000297	Psoralen	CHEMBL164660	D005363	12 / 6 / 6	0 / 5	No. 1282	No. 25
C00002463	Daphnoretin	CHEMBL508494	C035316	14 / 11 / 10		No. 1906	No. 25

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00000297 C00002463	3 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00000297 C00002463	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000297 C00002463	0 / 1
P56817	Beta-secretase 1	A1A	C00000297	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00000297	0 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00002463	1 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00000297	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00002463	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00000297	0 / 0
O75496	Geminin	Unclassified protein	C00002463	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00000297	0 / 0
P20813	Cytochrome P450 2B6	Cytochrome P450 2B6	C00000297	1 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00000297	1 / 0
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00002463	2 / 2
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00000297	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00000297	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00002463	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00002463	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002463	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00002463	4 / 3
Q9UBT6	DNA polymerase kappa	Enzyme	C00002463	0 / 0
P06746	DNA polymerase beta	Enzyme	C00002463	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00002463	1 / 1

OMIM	preferred title	UniProt
#300438	17-beta-hydroxysteroid dehydrogenase x deficiency	Q99714
#119900	Digital clubbing, isolated congenital	P15428
#609535	Drug metabolism, poor, cyp2c19-related	P33261
#608902	Drug metabolism, poor, cyp2d6-related	P10635
#614546	Efavirenz, poor metabolism of	P20813
#600274	Frontotemporal dementia; ftd	P10636
#259100	Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1	P15428
#300705	Mental retardation, x-linked 17; mrx17	Q99714
#300220	Mental retardation, x-linked, syndromic 10; mrxs10	Q99714
#160900	Myotonic dystrophy 1; dm1	Q9NR56
#260540	Parkinson-dementia syndrome	P10636
#172700	Pick disease of brain	P10636
#607250	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1	Q9NUW8
#601104	Supranuclear palsy, progressive, 1; psnp1	P10636

KEGG	name	UniProt
H00036	Osteosarcoma	P08684 (marker)
H00058	Amyotrophic lateral sclerosis (ALS)	P10636 (related)
H00077	Progressive supranuclear palsy (PSP)	P10636 (related)
H00078	Frontotemporal lobar degeneration (FTLD)	P10636 (related)
H01205	Coumarin resistance	P11712 (related)
H00457	Primary hypertrophic osteoarthropathy (PHO)	P15428 (related)
H01246	Isolated congenital nail clubbing (ICNC)	P15428 (related)
H01171	Poor drug metabolism (PM)	P33261 (related)
H00480	Non-syndromic X-linked mental retardation	Q99714 (related)
H00658	Syndromic X-linked mental retardation	Q99714 (related)
H00925	2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency	Q99714 (related)
H00063	Spinocerebellar ataxia (SCA)	Q9NUW8 (related)