Species

KNApSAcK Entry

Organism name Dacrydium franklinii
Genus Dacrydium
Family Podocarpaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lagarostrobos franklinii
Linked NCBI taxonomy ID 56892
Linked level species

Family

Family in NCBI taxonomy Podocarpaceae
ID 3362

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002741 External link 512 Methyleugenol
/ 4-Allylveratrole
/ Eugenol methyl ether
CHEMBL108861
C005223
12 / 13 / 9 3 / 9 No. 1412

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00002741 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00002741 3 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002741 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002741 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00002741 2 / 0
P04150 Glucocorticoid receptor NR3C1 C00002741 0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00002741 5 / 3
Q96RI1 Bile acid receptor NR1H4 C00002741 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002741 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002741 0 / 0
P10275 Androgen receptor NR3C4 C00002741 3 / 4
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00002741 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
2938 GSTA1, GST2, GSTA1-1, GTH1 glutathione S-transferase alpha 1 (EC:2.5.1.18) C00002741
2944 GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1 glutathione S-transferase mu 1 (EC:2.5.1.18) C00002741
2950 GSTP1, DFN7, FAEES3, GST3, GSTP, PI glutathione S-transferase pi 1 (EC:2.5.1.18) C00002741

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (13)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#114500 Colorectal cancer; crc P84022
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#601665 Obesity P37231
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (9)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)

Diseases related to CTD interactions

9 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000707 Anaphylaxis C00002741
D001943 Breast Neoplasms C00002741
D003328 Coronary Thrombosis C00002741
D006529 Hepatomegaly C00002741
D006930 Hyperalgesia C00002741
D008113 Liver Neoplasms C00002741
D008114 Liver Neoplasms, Experimental C00002741
D008325 Mammary Neoplasms, Experimental C00002741
D009374 Neoplasms, Experimental C00002741