Diospyros abyssinica

• Index
• Plant Species
• Metabolite list (5)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Diospyros abyssinica
Genus	Diospyros
Family	Ebenaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Diospyros abyssinica
Linked NCBI taxonomy ID	413718
Linked level	species

Family

Family in NCBI taxonomy	Ebenaceae
ID	19955

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (5)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003749	Lupeol / Lupenol / (+)-Lupenol	CHEMBL289191 CHEMBL459702	C010480	3 / 0 / 0	2 / 6	No. 23	No. 51
C00003741	Betulinic acid	CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635	C002070	34 / 17 / 14	10 / 2	No. 23	No. 51
C00003740	Betulin	CHEMBL23236 CHEMBL140040 CHEMBL1610940 CHEMBL2000891 CHEMBL2069124	C002503	18 / 16 / 17	0 / 2	No. 23	No. 51
C00002831	Isodiospyrin	CHEMBL1992900	C409666			No. 312
C00002816	Euclein / Diospyrin	CHEMBL242550	C043546			No. 312

Human Protein / Gene in interactions

39 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11387	DNA topoisomerase 1	Isomerase	C00003740 C00003741 C00003749	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003740 C00003741 C00003749	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003740 C00003741	0 / 0
P05771	Protein kinase C beta type	Alpha	C00003740 C00003741	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003740 C00003741	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00003740 C00003741	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003740 C00003741	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003740 C00003741	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00003740 C00003741	11 / 10
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003740 C00003741	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003740 C00003741	0 / 1
Q02156	Protein kinase C epsilon type	Eta	C00003740 C00003741	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003740 C00003741	0 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003740 C00003741	1 / 0
P15121	Aldose reductase	Enzyme	C00003741	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00003740	3 / 1
P08047	Transcription factor Sp1	Unclassified protein	C00003749	0 / 0
P08151	Zinc finger protein GLI1	Unclassified protein	C00003741	0 / 0
O75496	Geminin	Unclassified protein	C00003741	0 / 0
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	C00003741	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003741	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003741	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00003741	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00003741	1 / 1
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003741	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00003740	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003741	0 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003741	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00003740	0 / 3
P55055	Oxysterols receptor LXR-beta	NR1H3	C00003741	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003741	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00003741	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003741	2 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003740	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00003741	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003741	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003741	0 / 0
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00003741	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00003741	0 / 0

12 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00003741
581	BAX, BCL2L4	BCL2-associated X protein	C00003741
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003741
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003741
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003741
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003741
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003741
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003741
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00003741
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00003741
1499	CTNNB1, CTNNB, MRD19, armadillo	catenin (cadherin-associated protein), beta 1, 88kDa	C00003749
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00003749

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions