Scrophularia scorodonia
Species
KNApSAcK Entry
| Organism name | Scrophularia scorodonia |
|---|---|
| Genus | Scrophularia |
| Family | Scrophulariaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Scrophularia scorodonia |
|---|---|
| Linked NCBI taxonomy ID | 1053394 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Scrophulariaceae |
|---|---|
| ID | 4149 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00010569
|
Harpagide
|
CHEMBL430183
|
C033250
|
1 / 0 / 3 | No. 64 | No. 36 |
|
|
|
C00003075
|
Catalpol
|
CHEMBL513223
|
C078040
|
2 / 1 / 1 | 0 / 2 | No. 64 | No. 36 |
|
|
C00003073
|
Aucubin
|
CHEMBL514882
CHEMBL1873725 CHEMBL1874462 |
C006650
|
5 / 1 / 1 | No. 100 | No. 36 |
|
|
|
C00003083
|
Harpagoside
|
CHEMBL516702
CHEMBL464888 CHEMBL1525311 |
C033249
|
11 / 5 / 8 | No. 120 | No. 36 |
|
Human Protein / Gene in interactions
15 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00003083 C00010569 | 0 / 3 |
| P03372 | Estrogen receptor | NR3A1 | C00003073 C00003075 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003073 C00003083 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00003073 C00003083 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00003073 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003075 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003083 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003083 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003083 | 3 / 2 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003083 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003083 | 1 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003083 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003083 | 0 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00003073 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00003083 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
KEGG DISEASE (9)
| KEGG | name | UniProt |
|---|---|---|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00017 | Esophageal cancer |
P35354
(related)
|
| H00025 | Penile cancer |
P35354
(related)
|
| H00046 | Cholangiocarcinoma |
P35354
(related)
|