Species

KNApSAcK Entry

Organism name Gentiana rigescens
Genus Gentiana
Family Gentianaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Gentiana rigescens
Linked NCBI taxonomy ID 553056
Linked level species

Family

Family in NCBI taxonomy Gentianaceae
ID 21472

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00010604 External link 512 Loganic acid
CHEMBL1081585
CHEMBL1079678
CHEMBL1356464
CHEMBL1452775
C002947
6 / 8 / 7 No. 64 No. 36
C00010794 External link 512 Sweroside
CHEMBL456137
C049412
1 / 0 / 0 No. 806 No. 36
C00003100 External link 512 Swertiamarin
CHEMBL456138
C013270
1 / 0 / 0 No. 1348 No. 36
C00003082 External link 512 Gentiopicrin
/ Gentiopicroside
CHEMBL508320
C012997
2 / 2 / 0 0 / 1 No. 3781 No. 36
C00039260 External link 512 Gentirigenic acid
CHEMBL387932
No. 5380

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003082 C00010604 2 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00010604 4 / 3
O75496 Geminin Unclassified protein C00003100 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003082 0 / 0
P60033 CD81 antigen Unclassified protein C00010604 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00010604 0 / 0
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00010794 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00010604 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00010604 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#613496 Immunodeficiency, common variable, 6; cvid6 P60033
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (7)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00088 Common variable immunodeficiency (CVID) P60033 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D017114 Liver Failure, Acute C00003082