Species

KNApSAcK Entry

Organism name Lamium spp.
Genus Lamium
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lamium
Linked NCBI taxonomy ID 53158
Linked level genus

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006824 External link 512 Malonylshisonin
No. 7 No. 15
C00003083 External link 512 Harpagoside
CHEMBL516702
CHEMBL464888
CHEMBL1525311
C033249
11 / 5 / 8 No. 120 No. 36

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003083 1 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00003083 0 / 3
P16473 Thyrotropin receptor Glycohormone receptor C00003083 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003083 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00003083 0 / 0
O75496 Geminin Unclassified protein C00003083 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003083 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003083 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003083 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003083 0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00003083 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (8)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)