Species

KNApSAcK Entry

Organism name Stachybotrys chartarum
Genus
Family
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stachybotrys chartarum
Linked NCBI taxonomy ID 74722
Linked level species

Family

Family in NCBI taxonomy
ID

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (17)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00012672 External link 512 Verrucarin J
/ Muconomycin B
CHEMBL507752
CHEMBL576350
C035445
No. 84
C00012615 External link 512 Roridin D
/ 7'-Deoxo-2'-deoxy-2',3'-epoxy-7'-(1-hydroxyethyl)verrucarin A
C407766
No. 84
C00012619 External link 512 Roridine E
/ [2'E,7'R(R)]-2',3'-Didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl)-verrucarin A
CHEMBL337231
CHEMBL509175
C003797
No. 84
C00012626 External link 512 Satratoxin G
/ 2',3'-Epoxy-2',3'-dihydrosatratoxin H
C028268
2 / 1 No. 84
C00012627 External link 512 Satratoxin F
No. 84
C00012628 External link 512 Satratoxin H
C014184
0 / 1 No. 84
C00012671 External link 512 Verrucarin B
/ (2'S,3'R)-2'-Deoxy-2',3'-epoxyverrucarin A
CHEMBL1079296
No. 84
C00003195 External link 512 Trichodermin
CHEMBL1714827
CHEMBL2001648
D014243
7 / 4 / 4 No. 1091
C00012646 External link 512 Roridin C
/ Trichodermol
/ 12,13-Epoxy-trichothec-9-en-4beta-ol
CHEMBL2047177
No. 1262
C00036239 External link 512 Verrucarol
CHEMBL504718
C011140
No. 1262
C00036775 External link 512 Atranone A
No. 3912
C00036776 External link 512 Atranone B
No. 3912
C00036777 External link 512 Atranone C
No. 3912
C00036781 External link 512 Atranone G
/ (+)-Atranone G
No. 4572
C00036780 External link 512 Atranone F
/ (+)-Atranone F
No. 4572
C00036779 External link 512 Atranone E
/ (-)-Atranone E
No. 4603
C00036778 External link 512 Atranone D
/ (+)-Atranone D
No. 4603

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00003195 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003195 2 / 0
O75496 Geminin Unclassified protein C00003195 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003195 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003195 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003195 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003195 0 / 3

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
472 ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 ataxia telangiectasia mutated (EC:2.7.11.1) C00012626
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00012626

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#137800 Glioma susceptibility 1; glm1 O75874
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (4)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D019457 Chromosome Breakage C00012628
D000857 Olfaction Disorders C00012626