Species

KNApSAcK Entry

Organism name Achillea lanulosa
Genus Achillea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Achillea millefolium var. lanulosa
Linked NCBI taxonomy ID 282742
Linked level varietas

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003205 External link 512 Achillin
CHEMBL517040
CHEMBL1322934
CHEMBL1741501
C476810
12 / 7 / 10 No. 298 No. 38
C00020817 External link 512 Austricin
/ Desacetylmatricarin
/ 8-Deacetylmatricarin
CHEMBL1325998
CHEMBL1476276
CHEMBL1618787
CHEMBL1623213
CHEMBL1625152
C089156
No. 298 No. 38
C00020818 External link 512 Matricarin
/ Austricin acetate
CHEMBL2087220
No. 298 No. 38
C00020819 External link 512 Grossmisin
/ Hydroxyachillin
/ 8alpha-Hydroxyachillin
CHEMBL1325998
CHEMBL1476276
CHEMBL1618787
CHEMBL1623213
CHEMBL1625152
No. 298 No. 38
C00020820 External link 512 Acetoxyachillin
/ 8-Hydroxyachillin acetate
CHEMBL2087220
No. 298 No. 38

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003205 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003205 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00003205 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003205 2 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003205 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003205 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003205 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003205 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00003205 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003205 0 / 0
O00255 Menin Unclassified protein C00003205 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003205 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (10)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)