PCIDB

Telekia speciosa

Species

KNApSAcK Entry

Organism name Telekia speciosa
Genus Telekia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Telekia speciosa
Linked NCBI taxonomy ID 56539
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003306 External link 512 Isohelenin
/ Isoalantolactone
/ Isoallantolactone
CHEMBL273254
CHEMBL137803
CHEMBL1410671
CHEMBL1451900
CHEMBL2000732
C032787
6 / 4 / 5 No. 69 No. 38
C00012913 External link 512 Isotelekin
/ (+)-Isotelekin
CHEMBL2332641
No. 69 No. 38
C00012947 External link 512 Graveolide
/ (+)-Graveolide
/ 2,3-Dihydroaromaticin
/ [3aR-(3aalpha,4abeta,7aalpha,8alpha,9abeta)]-Decahydro-4a,8-dimethyl-3-methyleneazuleno[6,5-b]furan-2,5-dione
CHEMBL359555
CHEMBL1911138
CHEMBL1911140
3 / 0 / 0 No. 340 No. 38
C00021138 External link 512 8-epi-Confertin
CHEMBL359555
CHEMBL1911138
CHEMBL1911140
3 / 0 / 0 No. 340 No. 38
C00021080 External link 512 Carpesiolin
/ 6alpha-Hydroxy-2,3-dihydroaromaticin
CHEMBL81346
CHEMBL173460
CHEMBL273055
CHEMBL1171800
CHEMBL1644106
No. 340 No. 38
C00012916 External link 512 Telekin
/ Telekine
/ [3aR-(3aalpha,4aalpha,8abeta,9aalpha)]-Decahydro-4a-hydroxy-8a-methyl-3,5-bis(methylene)-naphtho[2,3-b]furan-2(3H)-one
CHEMBL406233
No. 658

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00012947 C00021138 0 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor C00012947 C00021138 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00012947 C00021138 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003306 1 / 1
P03372 Estrogen receptor NR3A1 C00003306 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003306 0 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003306 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003306 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003306 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8

KEGG DISEASE (5)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)